Of 31 children born of father–daughter matings, 6 diedin infancy, 12 were very abnormal and died in childhood, and 13 were normal. From this information, calculate roughly how many recessive lethal genes we have,on average, in our human genomes. (Hint: If the answerwere 1, then a daughter would stand a 50 percent chanceof carrying the lethal allele, and the probability of theunion’s producing a lethal combination would be 1/2 ×1/4 = 1/8. So 1 is not the answer.) Consider also the possibility of undetected fatalities in utero in such matings.How would they affect your result?

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
10th Edition
ISBN:9781305967359
Author:STARR
Publisher:STARR
Chapter13: Patterns In Inherited Traits
Section: Chapter Questions
Problem 6GP: In sweet pea plant, an allele for purple flowers (P) is dominant when paired with a recessive allele...
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Of 31 children born of father–daughter matings, 6 died
in infancy, 12 were very abnormal and died in childhood, and 13 were normal. From this information, calculate roughly how many recessive lethal genes we have,
on average, in our human genomes. (Hint: If the answer
were 1, then a daughter would stand a 50 percent chance
of carrying the lethal allele, and the probability of the
union’s producing a lethal combination would be 1/2 ×
1/4 = 1/8. So 1 is not the answer.) Consider also the possibility of undetected fatalities in utero in such matings.
How would they affect your result?

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