If 83% of the Elmo Muppet population has a condition that makes them refer to themselves in the third person, and you know that this condition is the result of the homozygous recessive genotype (ee)… You allow the Elmos to reproduce for a while and discover that in the heterozygous condition, the Elmos are capable of referring to themselves in the 3rd person, but only do so upon request. The PBS station puts out a casting call for a locally-produced Sesame Street. This is your chance to make a little cash with all the Elmos you have in your basement. It turns out, however, that the heterozygous Elmos are strongly preferred by the production crew, since they can turn off the third person self-references. So: EE Elmos are NOT acceptable actors, Ee Elmos are preferred actors, and ee Elmos are acceptable, but only when Ee Elmos are unavailable. If having a gig on Sesame Street is critical to Elmo survival: rank the fitness levels of the three genotypes and discuss whether/how long the E allele will persist in the population provide a real-life example of this type of scenario when a deleterious allele can have differential effects on survival depending upon genotype
If 83% of the Elmo Muppet population has a condition that makes them refer to themselves in the third person, and you know that this condition is the result of the homozygous recessive genotype (ee)…
You allow the Elmos to reproduce for a while and discover that in the heterozygous condition, the Elmos are capable of referring to themselves in the 3rd person, but only do so upon request. The PBS station puts out a casting call for a locally-produced Sesame Street. This is your chance to make a little cash with all the Elmos you have in your basement. It turns out, however, that the heterozygous Elmos are strongly preferred by the production crew, since they can turn off the third person self-references. So: EE Elmos are NOT acceptable actors, Ee Elmos are preferred actors, and ee Elmos are acceptable, but only when Ee Elmos are unavailable. If having a gig on Sesame Street is critical to Elmo survival:
- rank the fitness levels of the three genotypes and
- discuss whether/how long the E allele will persist in the population
- provide a real-life example of this type of scenario when a deleterious allele can have differential effects on survival depending upon genotype
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