OH CHO OH `OH ÓCH3 ÓCH3 2-Chloro-3-hydroxy- 4-methoxybenzaldehyde

Q: Predict the reagents for reactions A and B. A А - 1. DIBAH, 2. Hа0* B= 1. LIAIH4, 2. H30* A- 1.…

A: In organic chemistry, the addition of hydrogen atoms or the removal of oxygen atoms are generally…

Q: Capsaicin, the spicy component of hot peppers, can be prepared from amine X and acid chloride Y.…

A: Using (E)-6-methylhept-4-en-1-ol, CH2(CO2Et)2 and inorganic reagents the synthesis of Y is shown…

Q: What is the expected major product for the following reaction sequence? CH3 1. BD THF 2. H,O,NAOH OH…

A: Hydroboration–oxidation reaction: Alkene gives an electrophilic addition reaction with borane.…

Q: SH S-S 2 + 2HI

A: For the conversion of thiol to disulphides in the lab, we use Iodine in the presence of base  and…

Q: Which one of the following synthetic routes gives the best yield of meta-bromoaniline starting with…

A: Benzene is an organic compound with the molecular formula C6H6. Benzene possesses 3 carbon-carbon…

Q: The following molecule undergoes an intramolecular reaction in the presence of pyrrolidinium…

A:

Q: Reaction of phenol with acetone in the presence of an acid catalyst gives a compound known as…

A:

Q: Muscalure is the sex attractant of the common housefly. Flies are lured to traps filled with bait…

A: Muscalure can be synthesized from 1-bromopentane.

Q: 1/2 100% d. 5-chioro-410dopent-z-yne e. ortho-florophenol 3. Predict a product and Look at the…

A:

Q: 15. provide the missing reagents for the following reaction

A: The Grignard reaction: Alkyl, vinyl, or aryl-magnesium halides ( RMgBr) is called as Grignard…

Q: 11.4 Show how are the following alcohols prepared by the reaction of a suitable Grignard reagent on…

A:

Q: What reagents are needed to accomplish the following transformation? CH3 O 1- Hg(OAc)2, H₂O 2-…

A: When an alkene undergoes hydroboration Oxidation Reaction, then an alcohol is formed according to…

Q: What reagents are needed to convert each compound to benzaldehyde (CgHsCHO)? More than one step may…

A: a) C6H5CH2OH = The reagents needed to produce Benzaldehyde from the given reactant is,

Q: Indicate how the following compounds can be synthesized from cyclohexanone and any other necessary…

A: a.

Q: "redict the product for the following reaction. CH3OH/ H2SO4 mhich is the MAJOR product of the…

A:

Q: What major product will be formed when the shown Grignard reagent is combined with the shown…

A: Given reaction,

Q: 14) Which combination of reagents is the least effective in generating sodium ethoxide, CH3CH2ONA?…

A:

Q: 9. Provide a mechanism for the following transformation: H,Cro, он HO H,O

A: In presence of H2CrO4 , alcohol is oxidised to acid through the formation of aldehyde.

Q: What is the name of reaction 2?   a Grignard reaction   b Reduction   c Acetal formation   d…

A: Here we are name the reaction and the product formed.

Q: 1. What set of reagents is necessary for the synthesis of the following compound: A A В C D D CN CN…

A: Diels-Alder reaction: The Diels–Alder reaction is a pericyclic reaction (cycloaddition) between a…

Q: The so-called Wieland–Miescher ketone is a valuable starting material used in the synthesis of…

A: The Wieland-Miescher ketone analogue can be prepared by Robinson annulation.

Q: How would you prepare benzylamine (CeHsCH,NH) from each compound? In some cases, more than one step…

A: aC6H5CH2Br + HNH2à C6H5CH2NH2 + HBr   bC6H5CN  + 4H (Na + C2H5OH) à C6H5CH2NH2      c.Hoffmann’s…

Q: (Z)-6-Heneicosene-11-one Several syntheses of this compound have been reported, one of which is…

A: From given  All steps drawn separately and the synthesis is given as follows

Q: Draw a stepwise mechanism for the following reactions, two steps in R. B. Woodward’s classic…

A: Stepwise mechanism:

Q: But-2-ene-1-thiol is a component of skunk spray. How would you synthesize this substance from…

A: Under acidic condition nucleophile attacks on greater substituted carbon of epoxide while under…

Q: 3,5-dimethyl cyclopentene, on ozonolysis, yields: 1) only an aldehyde 3) an aldehyde and a ketone 4)…

A:

Q: Identify the needed reagents in the following scheme: Br CH2OH HO OH сно b. C. а. d. е. f. -1

A: here cyclohexanone is undergoing certain chemical reaction using different reagents to form trans…

Q: What is the best set of reagents to achieve deoxygenation of 2-pentanone to pentane? A.…

A: Deoxygenation is a complete reduction of 2-pentanone.

Q: 1. What reagents will accomplish the following multistep synthesis? A) HBr, CH,00CH3 B) HBr C)…

A:

Q: 65. Which set of reagents would complete the following transformation? CI A. 1) H2SO4, heat; 2)…

A: During the E2 elimination reaction, the structure of the product depends on the bulkiness of the…

Q: Identify reagents that can be used to achieve the following transformation: OH O 1) NaOH, 2) RCO3H,…

A:

Q: Identify the reagents required for the following transformation: HO o OSO4, NaHSO3, H20 O BH3, THF:…

A: In the above reaction, the alkene is converting into alcohol by the addition of H on the lower…

Q: What product is obtained when the following compound undergoes two successive elimination reactions?

A: The reactant with two halogens when undergoes two successive elimination reactions, it forms a…

Q: Reagents a. C6H5CHO b. NaOH, ethanol c. Pyrrolidine, cat. H* j. d. H2C=CHCN e. H30* f. LDA h.…

A: Michael addition : carbanion addition at beta position of α,β-unsaturated carboxylic acid…

Q: a) Draw the initial ENOL products for the two reactions below: Reaction 1: Reaction 2: CH3(CH₂)5C CH…

A: In the given question the same reactant is treated under two different conditions with two different…

Q: Which set of reagents are required for the following transformation? ОН ? Select one: 1. Hg(ОАc)2,…

A:

Q: Chose the reagents necessary to carry out the following conversion: „NH2 `CN LIAIH4 H2O O DIBAL O 1.…

A: 1)LiAlH4 is strong reducing agent it release H2 to readuce any functional group . 2) NaOC2H5 is base…

Q: 24. Which set of reagents would provide the best synthesis of ethyl t-butyl ether? (A) (CH3);CONA +…

A: Detail mechanistic pathway is given below

Q: 9.47 How can you explain the observation that the SN2 reaction of (dibromomethyl)benzene with NaOH…

A: SN2 reaction: It is the chemical reaction of nucleophilic substitution in which there will be…

Q: Which is a keto-enol tautomeric pair? し-ん し l OOH OH (b) OH (し (e) i. OH Give the starting material…

A: 1) The options given for keto-enol pairs are,

Q: Select the best combination of reagents for the following transformation. CI O 1. MeMgBr, 2. H2O O…

A: The question is based on the concept of organic reactions.   We have to identify in which of the…

Q: Which set of reagents would best accomplish the following transformation? reagent Ph Ph Br 單選: O a.…

A: The given reaction is the alpha halogenation of ketone. The alpha halogenation of ketone takes place…

Q: Reaction of p-bromobenzoic acid with KOH produces which of the following products? A) potassium…

A: Answer : A) potassium p-bromobenzoate

Q: What is the best choice of reagent(s) to perform the following transformation? * KOH, Ethanol and…

A:

Q: Reaction of benzylmagnesium chloride with formaldehyde yields alcohols N and P after protonation.…

A: The Grignard reagent is denoted as R-MgX, where R can an alkyl/aryl/ar-alkyl groups and X can be a…

Q: 1 Predict the product for the following transformation. Br 1. Me-PPH3 n-BuLi, THF 2. cat. Cp2La(NM…

A: These are the examples of imination of alkene and Haffman elimination

Q: (c) Reaction of acetanilide with bromine Br: CH3 (d) Hydrolysis of 4-bromo-2-chloroacetanilide with…

A:

Q: 3. Choose the reagents necessary to complete the following transformation. H, + H H. А. КMnO,, Но B.…

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Q: HE OCH, H,C The most reactive compound(s) towards nucleophilic acyl substitution reactions? H.C OH…

A: The compounds given are,

Q: Which of the shown reagents is needed to accomplish the shown reaction ? OCH3 NaOCH3 ??? DMF ´CH3 CI…

A: Nucleophilic substitution biomolecular reaction (SN2):The bimolecular nucleophilic substitution…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.