Orciprenaline (C11H17NO3, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. Read the following information carefully and answer the questions below. (Record your answers in decimal notation to the indicated significant figures OR decimal places) ASSAY – 20 tablets weighing 2.597 g

Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
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Chapter1: Basic Concepts Of Chemistry
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Orciprenaline (C11H17NO3, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. Read the following information carefully and answer the questions below. (Record your answers in decimal notation to the indicated significant figures OR decimal places)

ASSAY – 20 tablets weighing 2.597 g were crushed to a powder. A portion of the crushed powder (0.5456 g) was shaken with 50 mL of 0.1 M HCl, the mixture was filtered and made up to 100 mL. 10 mL of this solution was further diluted to 100 mL with 0.1 M HCl. The measured absorbance of the diluted solution at 276 nm was 0.582. Additional information: A1% = 72.3, stated content = 20 mg

Calculate:

a) The concentration of orciprenaline in the diluted solution in mg/L

 Calculate the answer by read surrounding text. mg/L (2 decimal places)

b) The actual amount of orciprenaline (in mg) in the powder assayed.

Calculate the answer by read surrounding text. mg (1 decimal place)

c) The actual amount of orciprenaline (in mg) per tablet.

Calculate the answer by read surrounding text.  mg (1 decimal place)

d) The percentage of stated content of per tablet.

Calculate the answer by read surrounding text. % (1 decimal places)

a-d

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