Part C Calculate to three decimal places the charge on a-melanotropin at pH value of 5. Express your answer using three decimal places. VE ΑΣΦ Submit Part D Request Answer Submit B Calculate to three decimal places the charge on a-melanotropin at pH value of 1. Express your answer using three decimal places. VE ΑΣΦ Request Answer ? www ?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Part C
Calculate to three decimal places the charge on a-melanotropin at pH value of 5.
Express your answer using three decimal places.
VE ΑΣΦ
Submit Request Answer
Part D
Calculate to three decimal places the charge on a-melanotropin at pH value of 1.
Express your answer using three decimal places.
VE ΑΣΦ
Submit
?
Request Answer
?
Transcribed Image Text:Part C Calculate to three decimal places the charge on a-melanotropin at pH value of 5. Express your answer using three decimal places. VE ΑΣΦ Submit Request Answer Part D Calculate to three decimal places the charge on a-melanotropin at pH value of 1. Express your answer using three decimal places. VE ΑΣΦ Submit ? Request Answer ?
Properties of some amino acids found in proteins
pKa of
lonizing Side
Chain
12.5
Name
Arginine
Aspartic
acid
Cysteine
Glutamic
acid
Abbreviations 1- and
3-letter
R, Arg
D, Asp
C, Cys
E, Glu
Histidine
H, His
Lysine
K, Lys
Tyrosine Y, Tyr
3.9
8.3
4.2
6.0
10.0
10.1
Approximate values found for side chains on the
free amino acids. W.P. Jencks and J. Regenstein
(1976) lonization constants of acids and based in
Handbook of Biochemistry and Molecular Biology,
3rd ed., G. Fasman (ed.), CRC Press, Boca Raton,
FL.
a-melanotropin (
Ser-Tyr -Ser -Met- Glu -His – Phe -Arg –Trp- Gly –Lys— Pro – Val),
given.
Lilla
values would you expect the
Assume the pKas of the N- and C-termini are 7.9 and 3.8, respectively. For side chains, assume the pKą values
Transcribed Image Text:Properties of some amino acids found in proteins pKa of lonizing Side Chain 12.5 Name Arginine Aspartic acid Cysteine Glutamic acid Abbreviations 1- and 3-letter R, Arg D, Asp C, Cys E, Glu Histidine H, His Lysine K, Lys Tyrosine Y, Tyr 3.9 8.3 4.2 6.0 10.0 10.1 Approximate values found for side chains on the free amino acids. W.P. Jencks and J. Regenstein (1976) lonization constants of acids and based in Handbook of Biochemistry and Molecular Biology, 3rd ed., G. Fasman (ed.), CRC Press, Boca Raton, FL. a-melanotropin ( Ser-Tyr -Ser -Met- Glu -His – Phe -Arg –Trp- Gly –Lys— Pro – Val), given. Lilla values would you expect the Assume the pKas of the N- and C-termini are 7.9 and 3.8, respectively. For side chains, assume the pKą values
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