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Part IV-Conclusion Suzanne and David did undergo two cycles of PGD. In the first cycle, the two embryos tested were found to have the mutated APP genes. In the second cycle, four unaffected embryos were put into Suzanne's uterus and one of those embryos successfully implanted. Genetic testing of this fetus through chorionic villi sampling at week 10 of the pregnancy confirmed that the baby did not have the APP mutation. Suzanne gave birth to a healthy baby girl in 2000. Questions 1. What are typical IVF success rates? Please explain. 2. Do insurance companies typically pay for IVF? Why or why not? Are there some "conditions" that are covered and others that are not? 3. What is chorionic villi sampling (cvs)? How is it generally accomplished? How does cvs compare to amniocentesis as a form of obtaining fetal genetic information? Are there risks involved in either of these testing types? 4. What are possible next steps for this family? What strategies/agencies, etc., will they need to help them cope?

Part IV-Conclusion Suzanne and David did undergo two cycles of PGD. In the first cycle, the two embryos tested were found to have the mutated APP genes. In the second cycle, four unaffected embryos were put into Suzanne's uterus and one of those embryos successfully implanted. Genetic testing of this fetus through chorionic villi sampling at week 10 of the pregnancy confirmed that the baby did not have the APP mutation. Suzanne gave birth to a healthy baby girl in 2000. Questions 1. What are typical IVF success rates? Please explain. 2. Do insurance companies typically pay for IVF? Why or why not? Are there some "conditions" that are covered and others that are not? 3. What is chorionic villi sampling (cvs)? How is it generally accomplished? How does cvs compare to amniocentesis as a form of obtaining fetal genetic information? Are there risks involved in either of these testing types? 4. What are possible next steps for this family? What strategies/agencies, etc., will they need to help them cope?

Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter16: Regulation Of Gene Expression
Section: Chapter Questions
Problem 8TYK
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Please help me answer questions Part IV- 1, 3, 4

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Heres a link to the PDF

https://www.cusd80.com/cms/lib/AZ01001175/Centricity/Domain/8922/eofad.pdf

Part IV-Conclusion Suzanne and David did undergo two cycles of PGD. In the first cycle, the two embryos tested were found to have the mutated APP genes. In the second cycle, four unaffected embryos were put into Suzanne's uterus and one of those embryos successfully implanted. Genetic testing of this fetus through chorionic villi sampling at week 10 of the pregnancy confirmed that the baby did not have the APP mutation. Suzanne gave birth to a healthy baby girl in 2000. Questions 1. What are typical IVF success rates? Please explain. 2. Do insurance companies typically pay for IVF? Why or why not? Are there some "conditions" that are covered and others that are not? 3. What is chorionic villi sampling (cvs)? How is it generally accomplished? How does cvs compare to amniocentesis as a form of obtaining fetal genetic information? Are there risks involved in either of these testing types? 4. What are possible next steps for this family? What strategies/agencies, etc., will they need to help them cope? Resources Gazit, C., and H.K. Steinman. 2006. Test Tube Babies. American Experience Series for the Public Broadcasting Service. http://www.pbs.org/wgbh/amex/babies/filmmore/index.html. Last accessed: 2/28/08. Hanna, K. January 2006. Reproductive Genetic Testing. National Human Genome Research Institute. National Institutes of Health. http://www.genome.gov/10004766. Last accessed: 2/28/08. Mayo Clinic Staff. April 12, 2006. Genetic Testing for Genetic Disorders: Weigh Benefits and Risks. http://www.mayoclinic.com/health/genetic-testing/FLooo76. Last accessed: 2/28/08. National Library of Medicine/National Institutes of Health. 2008. Prenatal Testing. http://www.nlm.nih.gov/medlineplus/prenataltesting.html. Last accessed: 2/28/08. Continually updated. Good website full of links to various sources of information-overviews, diagrams, specific procedures, and other information. Petrozza, J.C., and A.K. Styer. July 2006. Assisted Reproduction Technology. Published by eMedicine. http://www.emedicine.com/med/topic3288.htm. Last accessed: 2/28/08. Vayena, E., P.R. Rowe, and P.D. Griffin, eds. 2001. Current Practices and Controversies in Assisted Reproduction. World Health Organization report of a meeting held Sept 17-21, 2001. http://www.who.int/reproductive-health/infertility/report_content.htm. Last accessed: 2/28/08. Image credits: Title block image OPeteWill/iStockPhoto. Figures 1 and 2 courtesy of U.S. National Institutes of Health, http://www.nia. nih.gov/Alzheimers/Resources/HighRes.htm. Figure 3, licensed image Odra_schwartz/iStockPhoto. Figure 4. Wikimedia Commons, author "TransControl", used pursuant to the GNU Free Documentation License, http://en.wikipedia.org/wiki/Image:AgarosegelUV.jpg Case copyright ©2008 by the National Center for Case Study Teaching in Science. Originally published August 19, 2008 at http://www.sciencecases.org/cofad/cofad.asp. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work. "Living With Her Genes" by Gildensoph, Stanford, & Wygal Page 6
Transcribed Image Text:Part IV-Conclusion Suzanne and David did undergo two cycles of PGD. In the first cycle, the two embryos tested were found to have the mutated APP genes. In the second cycle, four unaffected embryos were put into Suzanne's uterus and one of those embryos successfully implanted. Genetic testing of this fetus through chorionic villi sampling at week 10 of the pregnancy confirmed that the baby did not have the APP mutation. Suzanne gave birth to a healthy baby girl in 2000. Questions 1. What are typical IVF success rates? Please explain. 2. Do insurance companies typically pay for IVF? Why or why not? Are there some "conditions" that are covered and others that are not? 3. What is chorionic villi sampling (cvs)? How is it generally accomplished? How does cvs compare to amniocentesis as a form of obtaining fetal genetic information? Are there risks involved in either of these testing types? 4. What are possible next steps for this family? What strategies/agencies, etc., will they need to help them cope? Resources Gazit, C., and H.K. Steinman. 2006. Test Tube Babies. American Experience Series for the Public Broadcasting Service. http://www.pbs.org/wgbh/amex/babies/filmmore/index.html. Last accessed: 2/28/08. Hanna, K. January 2006. Reproductive Genetic Testing. National Human Genome Research Institute. National Institutes of Health. http://www.genome.gov/10004766. Last accessed: 2/28/08. Mayo Clinic Staff. April 12, 2006. Genetic Testing for Genetic Disorders: Weigh Benefits and Risks. http://www.mayoclinic.com/health/genetic-testing/FLooo76. Last accessed: 2/28/08. National Library of Medicine/National Institutes of Health. 2008. Prenatal Testing. http://www.nlm.nih.gov/medlineplus/prenataltesting.html. Last accessed: 2/28/08. Continually updated. Good website full of links to various sources of information-overviews, diagrams, specific procedures, and other information. Petrozza, J.C., and A.K. Styer. July 2006. Assisted Reproduction Technology. Published by eMedicine. http://www.emedicine.com/med/topic3288.htm. Last accessed: 2/28/08. Vayena, E., P.R. Rowe, and P.D. Griffin, eds. 2001. Current Practices and Controversies in Assisted Reproduction. World Health Organization report of a meeting held Sept 17-21, 2001. http://www.who.int/reproductive-health/infertility/report_content.htm. Last accessed: 2/28/08. Image credits: Title block image OPeteWill/iStockPhoto. Figures 1 and 2 courtesy of U.S. National Institutes of Health, http://www.nia. nih.gov/Alzheimers/Resources/HighRes.htm. Figure 3, licensed image Odra_schwartz/iStockPhoto. Figure 4. Wikimedia Commons, author "TransControl", used pursuant to the GNU Free Documentation License, http://en.wikipedia.org/wiki/Image:AgarosegelUV.jpg Case copyright ©2008 by the National Center for Case Study Teaching in Science. Originally published August 19, 2008 at http://www.sciencecases.org/cofad/cofad.asp. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work. "Living With Her Genes" by Gildensoph, Stanford, & Wygal Page 6
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