PEDIGREES: Problem 7 This pedigree shows the inheritance of atype of X-linked color blindness. It is a recessive trait. Carriers have NOT been half-shaded in this pedigree.
Q: Please explain about X-linked recessive allele.
A: Sex-linked are those genes for which are present on either the X or Y chromosome.
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- Hi, I'm having trouble with my study guide for my upcoming genetics exam. If someone could please help with work shown and an explanation it would help so much! Thank you!! 2a. The pedigree below represents inheritance of rare condition. What pattern of inheritance is most consistent with the data? Assign alleles to all individuals to support your answer. If an allele is unknown, assign it a ? symbol. NOTE: Individuals whose phenotype or genotype cannot be determined are assumed to be unaffected and homozygous, unless otherwise indicated. 2b. In addition to the alleles you’ve indicated, describe 2 overall features of the pedigree that make it consistent with your chosen form of inheritance. 2c. Based on your mode of inheritance, what is the probability that the child of couple IV-4 x IV-5 will be affected? Show your work. attached is the pedigreeAnalysis of Autosomal Recessive and Dominant Traits Huntington disease is a rare, fatal disease that usually develops in the fourth or fifth decade of life. It is caused by a single autosomal dominant allele. A phenotypically normal man in his twenties who has a 2-year-old son of his own learns that his father has developed Huntington disease. What is the probability that he himself will develop the disease? What is the chance that his young son will eventually develop the disease?Crossing Pea Plants: Mendels Study of Single Traits Sickle cell anemia (SCA) is a human genetic disorder caused by a recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?
- Variations on a Theme by Mendel A characteristic of snapdragons amenable to genetic analysis is flower color. Imagine that a true-breeding red- flowered variety is crossed to a pure line having white flowers. The progeny are exclusively pink-flowered. Diagram this cross, including genotypes for all P1 and F1 phenotypes. What is the mode of inheritance? Let F = red and f = white.Crossing Pea Plants: Mendels Study of Single Traits An unspecified characteristic controlled by a single gene is examined in pea plants. Only two phenotypic states exist for this trait. One phenotypic state is completely dominant to the other. A heterozygous plant is self-crossed. What proportion of the progeny of plants exhibiting the dominant phenotype is homozygous?Analysis of Autosomal Recessive and Dominant Traits In the following pedigree, assume that the father of the proband is homozygous for a rare trait. What pattern of inheritance is consistent with this pedigree? In particular, explain the phenotype of the proband.
- Hi, I'm having trouble with my study guide for my upcoming genetics exam. If someone could please help with work shown and an explanation it would help so much! Thank you!! 1a. The pedigree below represents inheritance of rare condition (filled symbols used for affected individuals). Test the hypothesis of X-linked dominant inheritance by assigning alleles (A or a) to sex chromosomes of all individuals in generations I and II. Does the X-linked dominant hypothesis agree with the data? It not, indicate all at least 2 individuals by generation and number (e.g. II-8) that are not consistent with the genotype you’ve proposed for the individuals in generation I. 1b. Test the hypothesis of autosomal dominant inheritance by assigning alleles (A or a) to autosomes of all individuals in the pedigree (generations I – IV). Does the autosomal dominant hypothesis agree with the data? It not, indicate all individuals by generation and number (e.g. II-8) that are not consistent with the genotype….Certain forms of human color blindness are inherited as X-linkedrecessive traits. Hemizygous males are color-blind, but heterozygous females are not. However, heterozygous females sometimeshave partial color blindness.A. Discuss why heterozygous females may have partial color blindness.B. Doctors identified an unusual case in which a heterozygousfemale was color-blind in her right eye but had normal colorvision in her left eye. Explain how this might have occurred.As attached, is a pedigree related question. I have a question, is it correct that individual I 1 's phenotype is Ff (heterozygous) whereas individual I 2 is ff (recessive homozygous)? That would mean that the ratio of Widow's Peak: Straight hair(no widow's peak) would be 1:1 ? So the chances of getting a Widow's Peak is 50% ? Is this correct? Am I doing it right.
- Pedigree attached shows an autosomal recessive genetic disease. G is the normal allele and g is the disease-causing allele. Individual 1’s father is heterozygous (*) and his mother is homozygous dominant. Other individuals in the pedigree may be carriers, but are not marked. The question mark (?) indicates that you do not yet know anything about this individual’s phenotype with regard to the disease. part a) What is the probability that individuals 1 and 2 will have a child (5) who is a boy with the disease (the child is unborn and the sex is not yet known)? a)1/8 b)1/4 c)0 d)1/16 part b) What is the probability that the daughter (6) that individual 3 and 4 just had will have the disease? a)1/8 b)1/6 c)1/4 d)1/12Look at the pedigree below and answer the following questions related to the human genetic trait depicted in this pedigree. 1. Indicate whether the pattern of inheritance associated with this human trait is most likely to be (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited. You may assume that the gene is fully penetrant. Then, provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.BbRrppMm X bbRrPpMM: probability of producing an individual that is dominant for B & M and recessive for R and P?