Phosphoric acid is a triprotic acid with the pKa values pKa1=2.148, pKa2=7.198, and pKa3=12.375. You wish to prepare 1.000 L of a 0.0100 M phosphate buffer at pH 7.780. To do this, you choose to mix the two salt forms involved in the second ionization, NaH2PO4, and Na2HPO4, in a 1.000 L volumetric flask and add water to the mark. What mass of each salt will you add to the mixture? What other combination of phosphoric acid and its salts could be mixed to prepare this buffer? H3PO4 and Na3PO4 H3PO4 and Na2HPO4 NaH2PO4 and Na3PO4 Na2HPO4 and Na3PO4 H3PO4 and NaH2PO4

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter15: Acid–base Equilibria
Section: Chapter Questions
Problem 55P
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Phosphoric acid is a triprotic acid with the pKa values pKa1=2.148, pKa2=7.198, and pKa3=12.375.

You wish to prepare 1.000 L of a 0.0100 M phosphate buffer at pH 7.780. To do this, you choose to mix the two salt forms involved in the second ionization, NaH2PO4, and Na2HPO4, in a 1.000 L volumetric flask and add water to the mark. What mass of each salt will you add to the mixture?

What other combination of phosphoric acid and its salts could be mixed to prepare this buffer?

H3PO4 and Na3PO4
H3PO4 and Na2HPO4
NaH2PO4 and Na3PO4
Na2HPO4 and Na3PO4
H3PO4 and NaH2PO4
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