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Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 21P
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Mark true statements for SCFS
SCFS typically target CDK inhibitors.
SCFS typically target CDKS.
SCFS phosphorylate target proteins.
SCFS target phosphorylated proteins.
The F-box protein part of the SCF complex targets proteins for degradation by
adding F-proteins.
The F-box protein part of the SCF complex targets proteins using ubiquitation.
Ubiquitinated proteins move to the lysosome.
When a generic mitogen receptor is activated
the generic intercellular pathway is activated.
CDK-G1 cyclin is activated and ubiquitinates Rb
CDK-G1 cyclin is inactivated and Rb becomes active
| active Rb protein is phosphorylated by CDK-G1 cyclin and becomes inactive
inactive Rb protein is phosphorylated and becomes active
O active Rb protein becomes a transcription factor and activates genes
inactive Rb protein becomes a transcription factor and represses genes
| active Rb protein inactivates transcription factors and represses genes
inactive Rb protein releases transcription factors that activate genes
Transcribed Image Text:multiple select! thank you Mark true statements for SCFS SCFS typically target CDK inhibitors. SCFS typically target CDKS. SCFS phosphorylate target proteins. SCFS target phosphorylated proteins. The F-box protein part of the SCF complex targets proteins for degradation by adding F-proteins. The F-box protein part of the SCF complex targets proteins using ubiquitation. Ubiquitinated proteins move to the lysosome. When a generic mitogen receptor is activated the generic intercellular pathway is activated. CDK-G1 cyclin is activated and ubiquitinates Rb CDK-G1 cyclin is inactivated and Rb becomes active | active Rb protein is phosphorylated by CDK-G1 cyclin and becomes inactive inactive Rb protein is phosphorylated and becomes active O active Rb protein becomes a transcription factor and activates genes inactive Rb protein becomes a transcription factor and represses genes | active Rb protein inactivates transcription factors and represses genes inactive Rb protein releases transcription factors that activate genes
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