Please consider the figure below, parts A and B. A В 部蹈器 Gene B Gene C Gene B Normal Gene A Chromosome 12 Normal Chromosome Please consider figure A. a. Do these chromosomes come from a dividing or non-dividing cell? Give a reason for your answer. b. How many molecules of double stranded DNA will be present at anaphase I of a cell from this organism? Please consider figure B. A potentially carcinogenic mutation occurred on one of the chromosomes. The gene affected by the mutation codes for a protein involved in the repair of DNA damage. c. What is the correct term used to describe this chromosomal mutation? d. In terms of the development of cancer, is this a dominant or recessive mutation? Whut in in inbe

Please consider the figure below, parts A and B. A В 部蹈器 Gene B Gene C Gene B Normal Gene A Chromosome 12 Normal Chromosome Please consider figure A. a. Do these chromosomes come from a dividing or non-dividing cell? Give a reason for your answer. b. How many molecules of double stranded DNA will be present at anaphase I of a cell from this organism? Please consider figure B. A potentially carcinogenic mutation occurred on one of the chromosomes. The gene affected by the mutation codes for a protein involved in the repair of DNA damage. c. What is the correct term used to describe this chromosomal mutation? d. In terms of the development of cancer, is this a dominant or recessive mutation? Whut in in inbe

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

See similar textbooks

Similar questions

A female patient 19 years old, whose symptoms areanemia and internal bleeding due to a massive buildupof leukemic white blood cells, is diagnosed withchronic myelogenous leukemia (CML). Karyotypeanalysis shows that the leukemic cells of this patientare heterozygous for a reciprocal translocation involving chromosomes 9 and 22. However, none of thenormal, nonleukemic cells of this patient contain thetranslocation. Which of the following statements istrue and which is false?a. The translocation results in the inactivation (loss offunction) of a tumor-suppressor gene.b. The translocation results in the inactivation (loss offunction) of an oncogene.c. There is a 50% chance that any child of this patientwill have CML.d. This patient is a somatic mosaic in terms of thekaryotype.e. DNA extracted from leukemic cells of this patient,if taken up by normal mouse tissue culture cells,could potentially transform the mouse cells intocells capable of causing tumors.f. The normal function of the…
Colchicine is a chemical mutagen that inhibits the spindle formation and prevents anaphase, which retains the cell’s single restitution nucleus (doubled chromosome number). Suppose that an onion (2n=16) is subjected to three consecutive rounds of colchicine treatment, what will be the resulting chromosome number of the treated onion?
I. In humans, chromosome 16 sometimes has a heavilystained area in the long arm near the centromere. Thisfeature can be seen through the microscope but has noeffect on the phenotype of the person carrying it.When such a “blob” exists on a particular copy ofchromosome 16, it is a constant feature of that chromosome and is inherited.A couple conceived a child, but the fetus hadmultiple abnormalities and was miscarried. When thechromosomes of the fetus were studied, it was discovered that it had three copies of chromosome 16 (it wastrisomic for chromosome 16), and that two of thethree chromosome 16s had large blobs. Bothchromosome 16 homologs in the mother lacked blobs,but the father was heterozygous for blobs. Which parent experienced nondisjunction, and in which meioticdivision did it occur?
Prader-Willi syndrome and Angelman syndrome are both caused by deletion of a set of genes onchromosome 15. The symptoms of Prader-Willi syndrome are short stature, small hands andfeet, hypotonia (floppiness), hypogonadism, mild mental retardation, and an uncontrollabledesire to eat (polyphagia). Angelman syndrome is characterized by an intellectual anddevelopmental delay, sleep disturbances, seizures, hand-flapping and other jerky movements,frequent laughter or smiling, and usually a happy demeanor.Please explain how the deletion of the same set of genes can result in such different diseases. Inyour answer, be sure to discuss the role of genetic imprinting and epigenetics.
The centromere Group of answer choices A is a group of proteins that attach to the kinetochore. B is not present on the chromosomes of the daughter cells until anaphase. C is a region of DNA where sister chromatids associate with one another and where the kinetochore forms D is a group of proteins that attach to the mitotic spindle. E is a region of DNA where sister chromatids associate with one another
A normal chromosome A B C D * E F G H I J K has mutated toA B C F E * D G H I J K J K.This is an example of a _________________ chromosomal mutation. ( * denotes the centromere) Group of answer choices Pericentric inversion of DEF and tandem duplication of JK. Pericentric inversion of DEF and displaced duplication of JK Paracentic inversion of DEF and displaced duplication of JK. Paracentric inversion of DEF and tandem duplication of JK.
2. Healthy elephant somatic cells are 2n=56. How many chromosomes are in a daughter cell at the beginning of MEIOSIS II in elephants? Group of answer choices A. 28 un-replicated B. 28 replicated C. 56 un-replicated D. 56 replicated 3. While studying tumor cells, you notice that the histones of a particular chromosome have more acetyl groups bound to them in tumor cells, compared to the same chromosome in healthy cells. What would you expect for the amount of proteins encoded by genes on that chromosome in tumor cells compared to healthy cells? Group of answer choices A. Higher in tumor cells B. Lower in tumor cells C. Similar in tumor and healthy cells
The plant Haplopappus gracilis has a 2n of 4. A diploid cellculture was established and, at premitotic S phase, aradioactive nucleotide was added and was incorporatedinto newly synthesized DNA. The cells were then removed from the radioactivity, washed, and allowed to proceed through mitosis. Radioactive chromosomes or chromatids can be detected by placing photographic emulsionon the cells; radioactive chromosomes or chromatids appeared covered with spots of silver from the emulsion.(The chromosomes “take their own photograph.”) Drawthe chromosomes at prophase and telophase of the firstand second mitotic divisions after the radioactive treatment. If they are radioactive, show it in your diagram. Ifthere are several possibilities, show them, too.
A cytogeneticist is studying the cells from an abnormal female monkey. In some cells, she finds that both X-chromosomes are active (i.e. not packaged into a Barr body), although one of the X-chromosomes appears shorter. She also finds that one of the autosomes are packaged as a Barr body, and she suspects that a translocation event might have been involved. By referring to the mechanism of X-chromosome inactivation, explain the observations made by the scientist
In com, male sterility is controlled by maternal cytoplasmic elements. However, the presence of a nuclear fertility restorer gene (F_) restores fertility to male sterile lines. Using the following cardboard chips, simulate the crosses indicated below. Present your cross to your instructor for checking. After being checked, draw your simulated crosses in the spacesprovided below. Give the genotypes and phenotypes of the offspring in each cross, and properly label the nucleus and the cytoplasm of each individual in the crosses.Big white circular chips Male sterile cytoplasmBig peach circular chips Male fertile cytoplasmSmall peach circular chips FF nucleusSmall half-white-half-peach circular chips Ff nucleusSmall white circular chips ff nucleus a. male sterile female x FF maleExplain your results. b. male sterile female x Ff maleExplain your results.
On rare occasions, a chromosome can suffer a small deletionthat removes the centromere. When this occurs, the chromosome usually is not found within subsequent daughter cells.Explain why a chromosome without a centromere is not transmitted very efficiently from mother to daughter cells. (Note: Ifa chromosome is located outside the nucleus after telophase, itis degraded.)
In the eukaryotic nucleus during interphase, a strand of chromatin consisting of eight conserved histone proteins, and a short region of double-stranded DNA wrapped around them, is: A. properly referred to as the radial miniband B. properly referred to as the supersolenoid C. properly referred to as the chromosome D. properly referred to as the nucleosome E. properly referred to as the solenoid