Please read the scenario below, and then answer the question (in bold) that follows. Tay-Sachs disease is a fatal autosomal recessive disorder in children (usually by age 5) that causes a progressive degeneration of the central nervous system. This disease affects 1 in 3,500 newborns of European Ashkenazi Jewish ancestry in the U.S. population. What is the frequency of the recessive allele in the population? a. 0.0003 b. 0.0170 c. 0.0332 d. 0.9665 e. 0.9830

Please read the scenario below, and then answer the question (in bold) that follows. Tay-Sachs disease is a fatal autosomal recessive disorder in children (usually by age 5) that causes a progressive degeneration of the central nervous system. This disease affects 1 in 3,500 newborns of European Ashkenazi Jewish ancestry in the U.S. population. What is the frequency of the recessive allele in the population? a. 0.0003 b. 0.0170 c. 0.0332 d. 0.9665 e. 0.9830

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 7QP: Use the following information to respond to the three questions posed below: (1) The proband...

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Please read the scenario below, and then answer the question (in bold) that follows. Tay-Sachs disease is a fatal autosomal recessive disorder in children (usually by age 5) that causes a progressive degeneration of the central nervous system. This disease affects 1 in 3,500 newborns of European Ashkenazi Jewish ancestry in the U.S. population. What is the number of carriers in the population? a. 1 person b. 60 persons c. 116 persons d. 3,383 persons e. 3,441 persons
Using the two equations, p + q = 1 and p2 + 2pq + q2 = 1, answer the following questions. Maple Syrup Urine Disease (MSUD) is an autosomal recessive condition that causes intellectual and physical disabilities, difficulty feeding, and a sweet maple syrup odor to the urine. In Costa Rica, the incidence of MSUD is calculated as approximately 1 in 8,000 newborns. Calculate the allele frequencies for the normal and disease alleles.
A given autosomal locus has three possible alleles (A1, A2, and A3). Assuming that the numbers of individuals with the six possible genotypes are as follows, what would be the frequency of the A1 allele in the population? A1A1 = 30 A1A2 = 27 A2A2 = 12 A1A3 = 17 A2A3 = 10 A3A3 = 4 What is the frequency of A1 allele in the population? A. 0.375 B. 0.52 C. 0.305 D. 0.175 E. 0.74
A gene has two alleles that are associated with body mass in an additive manner. The table below shows the mean phenotype for each genotype, along with the frequency of each genotype in a population. Use this information to answer the following questions. A1A1 A1A2 A2A2 Mean mass (kg) 50 55 60 Frequency 0.01 0.18 0.81 a) How much does this locus contribute to additive genetic variation? b)A second locus (B) has two alleles (B1 and B2), which are also associated with body mass in an additive manner. Each copy of the B2 allele adds 2 kg of mass. The B2 allele is at a frequency of 0.6 in the same population as the A alleles are found. How much does the B locus contribute to additive genetic variation? c) Assume that these two loci are the only sources of additive genetic variance for body mass. The total phenotypic variance for body mass in the population is 10 kg2. What is the narrow sense heritability (h2) of body mass in this population? d)…
A gene has two alleles that are associated with body mass in an additive manner. The table below shows the mean phenotype for each genotype, along with the frequency of each genotype in a population. Use this information to answer the following questions. A1A1 A1A2 A2A2 Mean mass (kg) 50 55 60 Frequency 0.01 0.18 0.81 a) How much does this locus contribute to additive genetic variation? b)A second locus (B) has two alleles (B1 and B2), which are also associated with body mass in an additive manner. Each copy of the B2 allele adds 2 kg of mass. The B2 allele is at a frequency of 0.6 in the same population as the A alleles are found. How much does the B locus contribute to additive genetic variation?
Please read the scenario below and answer the question (in bold) that follows: In humans, the ability to roll one's tongue is a dominant trait (T). A woman who can roll her tongue is married to a man who cannot roll his tongue. The couple's daughter, Nia, can roll her tongue though their son, Michael, cannot. If Nia were to (one day) marry a man who was heterozygous for the tongue-rolling trait, what percentage of their children would be able to roll their tongues? a. 0% b. 25% c. 50% d. 75% e. 100% M
If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol. ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.
If 120 of 200 alleles are dominant alleles, then what percentage of the alleles are dominant alleles? A-12% B-40% C-60% D-120% What percentage of the alleles are recessive alleles? E-8% F-40% G-60% H-80% Which of the terms of the Hardy-Weinberg equations represents the frequency of the recessive allele in the gene pool? A-p^2 B-p C-2pq D-q^2
If 60 percent of the loci in a gene pool are dominant for the hair color trait H, and 40 percent are recessive (h), then according to Hardy-Weinberg theory, what percentage of the individuals in the population will be recessive for this trait (hh)? A. 16 B. 40 C. 36 D. 24
A form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder. Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? A form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. Part a: In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder. Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? a)0.005 b)0.995 c)0.07 d)0.93 Part b: What is the estimated total number of homozygous dominant individuals in this village of 1000 people? a) 70 b) 930 c) 860 d) 140
Identify each of the following as an example of allele, genotype, and/or phenotype frequency: A. Approximately 1 in 2500 people of Northern European descent is born with cystic fibrosis. B. The percentage of carriers of the sickle cell allele in West Africa is approximately 13%. C. The number of new mutations for achondroplasia, a genetic disorder, is approximately 5 × 10–5.
PLEASE ANSWER THE QUESTION AND EXPLAIN SUCCINTLY IN 2 SENTENCES Why does inbreeding lead to an increase in recessive deleterious traits (for example inbreeding depression)?