Price et al. [(1999). J. Bacteriol. 181:2358–2362] conducteda genetic study of the toxin transport protein (PA) of Bacillusanthracis, the bacterium that causes anthrax in humans. Withinthe 2294-nucleotide gene in 26 strains they identified five pointmutations—two missense and three synonyms—among differentisolates. Necropsy samples from an anthrax outbreak in 1979revealed a novel missense mutation and five unique nucleotidechanges among ten victims. The authors concluded that thesedata indicate little or no horizontal transfer between differentB. anthracis strains. Question: On what basis did the authors conclude that evidence ofhorizontal transfer is absent from their data?

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Price et al. [(1999). J. Bacteriol. 181:2358–2362] conducted
a genetic study of the toxin transport protein (PA) of Bacillus
anthracis, the bacterium that causes anthrax in humans. Within
the 2294-nucleotide gene in 26 strains they identified five point
mutations—two missense and three synonyms—among different
isolates. Necropsy samples from an anthrax outbreak in 1979
revealed a novel missense mutation and five unique nucleotide
changes among ten victims. The authors concluded that these
data indicate little or no horizontal transfer between different
B. anthracis strains.

Question: On what basis did the authors conclude that evidence of
horizontal transfer is absent from their data?

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