Procaine (its hydrochloride is marketed as Novocain) was one of the first local anesthet-ics for infiltration and regional anesthesia. See "Chemical Connections: From Cocaineto Procaine and Beyond."According to the following retrosynthetic scheme, procainecan be synthesized from 4-aminobenzoic acid, ethylene oxide, and diethylamine assources of carbon atoms.HO.+ HONEt,H,NH,N'Procaine4-Aminobenzoic acidEt,NHEthylene oxide DiethylamineProvide reagents and experimental conditions to carry out the synthesis of procainefrom these three compounds.

The reagents and the reaction conditions to carry out the synthesis of procaine is given below:

Answered: Procaine (its hydrochloride is marketed…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.42P

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