Propose a reasonable biosynthesis for compound 34 starting from acetyl CoA, alanine CoA, malonyl CoA and valine methyl ester. H,C CH3 H,C. CH3 CH3 34
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- Outline the steps involved in the production of malonylCoA from acetyl-CoA.Name some HMG CoA reductase inhibitors? Please answer at your own words.Shemin and coworkers used acetatelabeling experiments to conclude that succinyl-CoA is a key intermediate in the biosynthesis of heme. Identify the intermediates in the conversion of acetate into succinyl-CoA.
- The sources of the three (3) carbons in malonyl-Coa is/are: a. 1 C from C02 and 2 C from acetyl-CoA b. 1 C from HCO3- and 2 C from acetyl-CoA c. 1 C from biotin and 2 C from acetyl-CoA d. All three C from acetyl-CoAThe reaction of acetyl-CoA and oxaloacetate in the TCA cycle forms a. 5-carbon α-ketoglutarate b. 4-carbon Succinyl-CoA c. 6-carbon citrate d. 6-carbon α-ketoglutarate e. 4-carbon citrateIn Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C. lactate only D. ethanol only
- options are Pyruvate, coenzyme A and NAD CO2, Acetyl CoA, NADH and H+ Acetyl CoA and oxaloacetate 2 COC 1 ATP, 3 NADH, and 1 FADH2Complete the following paragraph describing the fate of the second 14CO-acetyl-CoA molecule incorporated into the glyoxylate cycle. The glyoxylate produced in the isocitrate reaction combines with a (A.) 2nd molecule of oxoaloacetate, B.) 2nd molecule of succinate, C.)2nd molecule of acetyl coa) in the malate synthase reaction. Malate is (A.Chiral, B.diasteromeoic C.)Achiral) ; therefore, the oxaloacetate produced from glyoxylate will be labeled at (A.Either of carboxylate carbon B. specifically at methylene carbon C. Specifically at carbonyl carbon D. Specifically at carboxylate carbon bonded to methylene).Where is the labeled carbomn found when the folliowing molecules are added to a cell carrying out palmitate synthesis. A.) biocarbonate with labelled carbon. B.) Acetyl-Coa with labeled methyl carbon
- Which of the following intermediates are shared by ketone body synthesis and cholesterol biosynthesis? a) HMG-CoA b) Mevalonate c) Bothaandb d) NeitheranorbWhich of the following biochemical conversions can be carried out by the least number of proteins? Assume proper metabolic conditions, abundance of cofactors, necessary accessory molecules, etc. 1 propionyl-CoA → 1 succinyl-CoA 1 palmitate (16:0) → 8 acetyl-CoA 1 acetyl-CoA + 7 malonyl-CoA → 1 palmitate (16:0) 1 palmitate (16:0) → 1 acetyl-CoA + 1 myristic acid (14:0) 1 acetyl-CoA → 1 succinate Please answer very soon will give rating surelyList the steps and the enzyme in each step in the biosynthesis of palmatic acid using acetyl-CoA as starter compound.