Q3. Consider the ring closing metathesis (RCM) sequence used for the synthesis of macrocycle E and answer Parts (a) and (b). E F НО. OH G H (a) How could you convert unsaturated ester F into E (two steps are required, give conditions/reagents but not mechanisms)? (b) Disconnect ester F, showing the synthons to lead to equivalents G and H. Give the conditions for the forward synthesis

Q3. Consider the ring closing metathesis (RCM) sequence used for the synthesis of macrocycle E and answer Parts (a) and (b). E F НО. OH G H (a) How could you convert unsaturated ester F into E (two steps are required, give conditions/reagents but not mechanisms)? (b) Disconnect ester F, showing the synthons to lead to equivalents G and H. Give the conditions for the forward synthesis

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter21: Nas: Nucleophilic Aromatic Substitution

Section: Chapter Questions

Problem 7E

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