Rank the following carboxylic acid derivatives in decreasing order (most to least) of reactivity towards nucleophilic substitution CI NH2 OCH3 ONa II IV O I> IV> III > I| O > IV > || > I OI> III > || > IV O II > IV > 1> II

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.SE: Something Extra
Problem 25MP: Acid-catalyzed hydrolysis of a nitrile to give a carboxylic acid occurs by initial protonation of...
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Rank the following carboxylic acid derivatives in decreasing order (most to least) of reactivity towards nucleophilic substitution
CI
NH2
OCH3
ONa
II
IV
OI> IV> III > ||
O > IV > || >I
O I> II| > || > IV
O II > IV > 1> I
Transcribed Image Text:Rank the following carboxylic acid derivatives in decreasing order (most to least) of reactivity towards nucleophilic substitution CI NH2 OCH3 ONa II IV OI> IV> III > || O > IV > || >I O I> II| > || > IV O II > IV > 1> I
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