1. H2N но NH2 NH3 Cl 2. но a -Proton transfei b Lewis acid/base c-E2 elimination d SN2 Nucleophilic substitution e Electrophilic aromatic substitution f Carbonyl nucleophilic addn g-Nucleophilic subs at carbonyl(acyl Xfer) h-Conjugate (nucleophilic) addn Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. l.

1. H2N но NH2 NH3 Cl 2. но a -Proton transfei b Lewis acid/base c-E2 elimination d SN2 Nucleophilic substitution e Electrophilic aromatic substitution f Carbonyl nucleophilic addn g-Nucleophilic subs at carbonyl(acyl Xfer) h-Conjugate (nucleophilic) addn Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. l.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter13: Substitution

Section: Chapter Questions

Problem 4E

See similar textbooks

Similar questions

In SN2 reactions of haloalkanes, the order of reactivity is RI>RBr>RCl>RF. Alkyl iodides are considerably more reactive than alkyl fluorides, often by factors as great as 106. All 1-halo-2,4-dinitrobenzenes, however, react at approximately the same rate in nucleophilic aromatic substitutions. Account for this difference in relative reactivities.
Below is the equation for a nucleophilic substitution reaction and some experimental data. CH3CH2Br + CH3COO- ⇌ CH3CH2CO2CH3 + Br- Rate = k [CH3CH2Br][CH3COO-] Which mechanism would best fit the data?
Please provide 3 possible mechanisms for bromination of trans-cinnamic acid and pyridinium tribromide (Br2) with stereochemistry (wedge and dash bond) (1 for anti addition, 1 for syn addition, and 1 for 50:50 syn and anti additon).
Rank the following species from best nucleophile to poorest nucleophile in an aqueous solution:
Alkyl diazonium salts (shown below) are considered "super" leaving groups; a consequence of this is that they tend to be contact explosives What quailities make alkyl diazonium salts such excellent leaving groups?
In Image 4 predict the effect the substituent attached to the benzene ring would have on electrophilic aromatic substitution reactions? a.ortho/para director, deactivator b.ortho/para director, activator c.meta director, activator d.meta director, deactivator
Rank the nucleophiles in each group in order of increasing nucleophilicity.a. -OH, -NH2, H2Ob. -OH, Br-, F- (polar aprotic solvent)c. H2O, -OH, CH3CO2-
select the most appropriate reagent(s) to effect the change. 1. Disiamylborane, 2. HO–, H2O, H2O2 H2, Pd K2Cr2O7, H+ NaOCl H2SO4, HgSO4
Organic Chemistry - nucleophilic substitution and elimination rxns chapter
For each of the following reactions diagram the steps from the substrate to the product. For each step, a) over the reaction arrow supply the needed reagents b) name the type of reaction/mechanism {ROS (SN1, SN2, radical) E(E1, E2) A [acid-base, addition (carbocation, onium bridge, radical)]}
what is the forward reaction follwing the arrow whilst stating the reagents by doing retrosynthetic analysis of the final product
Organometallic reagents and alkoxides are strong bases as well as being good nucleophiles. Given the pKa values below, which reagent is the stronger base, nBuLi (CH3CH2CH2CH2LI) or the tert-butoxide anion ((CH3)3CO‒)? Explain your choice clearly in terms of structure andbonding. (Comparing the pKa values is not an explanation.) (CH3)3COH pka= 16.54CH3CH2CH2CH3 pka= 50