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reate a diagram which illustrates the typical signaling mechanism of action of g protein coupled land possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands

reate a diagram which illustrates the typical signaling mechanism of action of g protein coupled land possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands

Biochemistry
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 9P
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Create a diagram which illustrates the typical signaling mechanism of action of g protein coupled land possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway.
Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? What are the physiological processes involved? Is this autocrine, Key physiological paracrine or endocrine or some combination of them? What is the pathology of the receptor? process involved What are the downstream actions of the receptor? Which molecules does it interact with, how, and to what effect? How rapidly doe the effects appear? Mechanism of action Give one key journal reference in Vancouver format that describes the mode of action of the receptor Key reference O Focus Fnolish (United Kingdom)
Transcribed Image Text:Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? What are the physiological processes involved? Is this autocrine, Key physiological paracrine or endocrine or some combination of them? What is the pathology of the receptor? process involved What are the downstream actions of the receptor? Which molecules does it interact with, how, and to what effect? How rapidly doe the effects appear? Mechanism of action Give one key journal reference in Vancouver format that describes the mode of action of the receptor Key reference O Focus Fnolish (United Kingdom)
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