Required information Genes A and B are close together on the same chromosome. The figure shows two A BI ab cells during meios meiosis events occur as shown at left, with no crossing-over between genes A and B. Only a few meiosis event= shown at right, with a crossover between the two genes. AB AB AB A B ab ab a No crossing-over between A and B Crossing-over between A and B gametes produced by the A B/abindividual, which are parental?

Required information Genes A and B are close together on the same chromosome. The figure shows two A BI ab cells during meios meiosis events occur as shown at left, with no crossing-over between genes A and B. Only a few meiosis event= shown at right, with a crossover between the two genes. AB AB AB A B ab ab a No crossing-over between A and B Crossing-over between A and B gametes produced by the A B/abindividual, which are parental?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter3: Transmission Of Genes From Generation To Generation

Section: Chapter Questions

Problem 29QP

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This problem leads you through the derivation of acorrected equation for RF in yeast tetrad analysis thattakes into account double crossover (DCO) meioses. A yeast strain that cannot grow in the absence ofthe amino acid histidine (his−) is mated with a yeaststrain that cannot grow in the absence of the aminoacid lysine (lys−). Among the 400 unordered tetrads resulting from this mating, 233 were PD, 11 wereNPD, and 156 were T.a. What types of spores are in the PD, NPD, andT tetrads?b. Are the his and lys genes linked? How do you know? c. Using the simple equation RF = 100 × [NPD +(1/2)T]/total tetrads, calculate the distance in mapunits between the his and lys genes.d. If you think about all the kinds of meiotic eventsthat could occur (refer to Fig. 5.24), you can seethat the calculation you did in part (c) may substantially underestimate RF. What kinds of meioses(NCO, SCO, or DCO) generated each of the tetradtypes in this cross? e. What incorrect assumptions does the simple RFequation…