Q9: RNase is an enzyme that cleaves the P-05 bond in RNA. It has two His residues in the active site. Suggest a plausibleexplanation why the enzyme activity changes when pH is increased or decreased from pH 6.0, as shown in the graph.Activity (%)120100806040200010PHData provided by Dr. Sunita Chowrira, University of British Columbia.Choose all of the true statements.There are two His residues and both aredeprotonated below pH 4.2.The substrate is affected by the change in pH and isinactive (postively charged) when pH is above 6.0.RNAse is an acid-base catalyst.The RNase reaction is an example of metal ioncatalysis with a positively charged metal.Both His residues are deprotonated at pH higherthan than 6.5.

RNAse enzymes catalyse the breakdown of RNA molecules, which is essential for the cellular…

Answered: RNase is an enzyme that cleaves the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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