Steroid hormone receptors have different cellular locations. The progesterone receptor is located in the nucleus and interacts with DNA once progesterone has bound. But the glucocorticoid receptor is located in the cytosol and does not move into the nucleus until its ligand has bound. What structural feature must be different in these two receptor molecules?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
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Steroid hormone receptors have different
cellular locations. The progesterone
receptor is located in the nucleus and
interacts with DNA once progesterone has
bound. But the glucocorticoid receptor is
located in the cytosol and does not move
into the nucleus until its ligand has bound.
What structural feature must be different in
these two receptor molecules?
Transcribed Image Text:Steroid hormone receptors have different cellular locations. The progesterone receptor is located in the nucleus and interacts with DNA once progesterone has bound. But the glucocorticoid receptor is located in the cytosol and does not move into the nucleus until its ligand has bound. What structural feature must be different in these two receptor molecules?
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