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A: signal to be sent down an axon of a nerve cell, an action potential must be generated.
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- A drug binds to a receptor and causes an immediate change in the electrical signaling or excitability of that cell, without activating another signaling molecule. What type of receptor is this drug most likely binding to? G-protein coupled receptor (GPCR) Ligand-gated ion channel Enzyme-coupled receptor Intracellular receptor Voltage-gated ion channelFor a signal to be sent down an axon of a nerve cell, an action potential must be generated. This is done by.. Select one: a. G-protein coupled receptors bind ligand, a phosphorylation cascade occurs, this causes a change in charge of the membrane due to the addition of phosphates allowing Na+ channels to open. b. Ligand-gated K+ channels open, allowing K+ to rush out of the cell and depolarize that part of the membrane. This change in charge opens neighboring voltage-gated channels. c. Ligand-gated Na+ channels open, allowing Na+ to rush in. This then depolarizes that region of the membrane resulting in opening neighboring voltage-gated channels. d. Receptor tyrosine kinases have two Na+ molecules bind, this opens voltage-gated channels allowing the “signal” to pass down the axon.After it has been activated a G-protein _______. moves along the inside of the cell's membrane and activates enzymes binds to its receptor in the cell's nucleus and initiates translation travels in the bloodstream to its target cell and then binds to its receptor binds to a receptor on a nearby cell and then activates multiple proteins
- Each adenylyl cyclase molecule produces many cAMP molecules in an example of (a) receptor up-regulation (b) receptor down-regulation (c) signal amplification (d) scaffolding (e) similarities produced by evolutionAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorPut the steps of the process of G-protein signal transduction in the order (1-4) in which they occur. Second messenger molecules are activated and amplify the signal A signal molecule binds to a receptor on the outside of the cell The alpha (a) subunit of the G-protein inside the cell moves and binds to a nearby enzyme The receptor changes shape, transducing the signal into the cell
- When a signaling molecule binds with a receptor, (a) G proteins are inactivated (b) a third messenger is activated (c) cell signaling is terminated (d) cAMP is produced by the receptor (e) the receptor becomes activatedAmplification of a chemical signal occurs when? a. phosphorylation of proteins by protein kinase receptors is balanced by the immediate removal of phosphate groups by phosphatases b. a receptor in the plasma membrane activates several “first messenger” molecules while a signal molecule is bound to it c. a cAMP molecule activates one protein kinase molecule before being converted to AMP d. a receptor activates a single first messenger and a single second messengerWhen a signal binds to the Tyrosine kinase receptor (RTK), you have studied that a list of events occur sequentially. Map the events in the correct order from 1st to the last step.
- Which of the following best describes the type of receptor a beta-antagonist drugs acts on a.Ligand-regulated transmembrane enzymes b.Ion channel c.G protein-coupled receptor d.Intracellular lipid-soluble signalingIn the cAMP second messenger pathways, Protein kinase A is directly activated by _________. A) Group of answer choices B) cAMP C) Phosphorylation D) a G protein E) a G protein coupled receptor F) an enzymeAn unknown ion is flowing out of a neuron, creating an inhibitory response. This unknown ion must... Multiple choices A. Create an end plate potential B. be negatively charged C. be positively charged D. be highly concentrated outside of the neuron E. Be a result of a metabotropic signaling cascade