Question
  1. Suppose, you want to detect the CAG repeat expansion within a particular gene (30 repeats in normal changes to 250 repeats in disease) in a certain disease. How will you diagnose this disease condition? 
  2. Can you identify Y chromosome microdeletion (which involves the deletion of AZF locus) using conventional karyotyping? If not, then why? 
  3. How will you diagnose a chromosomal translocation event? (Discuss any one of the processes) 

 

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