tem 35 Organic cofactors are referred to as _________. Fill in the blank Item36   Item   Item 36   Noncompetitive inhibition of an enzyme occurs when the inhibitor binds to the   Multiple Choice   a. allosteric site, and its effectiveness is not influenced by substrate concentration.   b. allosteric site, and its effectiveness depends on substrate concentration.   c. active site, and its effectiveness is not influenced by substrate concentration.   d. active site, and its effectiveness depends on substrate concentration.   e. substrate, and its effectiveness depends on product concentration.   Item37       Item 37 A substance that binds to the active site of an enzyme and turns it off is called a _________ inhibitor. Fill in the blank     Item 38 Lactase is an enzyme that digests lactose. True or False     Item 39 Exergonic reactions do not require activation energy. True or False

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Item 35

Organic cofactors are referred to as _________.

Fill in the blank
Item36
 
Item
 

Item 36

 

Noncompetitive inhibition of an enzyme occurs when the inhibitor binds to the

 

Multiple Choice
 
a. allosteric site, and its effectiveness is not influenced by substrate concentration.
 
b. allosteric site, and its effectiveness depends on substrate concentration.
 
c. active site, and its effectiveness is not influenced by substrate concentration.
 
d. active site, and its effectiveness depends on substrate concentration.
 
e. substrate, and its effectiveness depends on product concentration.
 
Item37
 
 
 

Item 37

A substance that binds to the active site of an enzyme and turns it off is called a _________ inhibitor.

Fill in the blank
 
 

Item 38

Lactase is an enzyme that digests lactose.

True or False
 
 

Item 39

Exergonic reactions do not require activation energy.

True or False
Expert Solution
Step 1

A cofactor is the non-protein component of an enzyme that is necessary for the enzyme to perform its enzymatic activity. Cofactors can be inorganic ions and organic molecules. Organic cofactors enzymes are called coenzymes.

Noncompetitive inhibition occurs when the inhibitor binds to the enzyme other than the active site. The conformational change caused due to inhibitor binding leads to inhibition of enzymatic activity. This type of inhibition is also called allosteric inhibition and substrate concentration has no effect on inhibition.

An inhibitor may bind to an enzyme and block binding of the substrate is called competitive inhibition, since in such a situation the inhibitor “competes” with the substrate for binding to the enzyme.

Lactase breaks down the lactose in food and enables absorption of lactose in the body. Insufficient production of lactase leads to lactose intolerance.  

Exergonic reactions are characterized by negative change in free energy and there is a net release of energy due to the reaction. However. activation energy might still be necessary in order for the reaction to be initiated.

 

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