The amino acid histidine has a side chain for which the pKa 6.0. Calculate what fraction of the histidine side chains will carry a positive charge at pH 5.4.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter27: Amino Acids And Proteins
Section: Chapter Questions
Problem 27.45P
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The amino acid histidine has a side chain for which the pKa 6.0. Calculate what fraction of the histidine side chains will carry a positive charge at pH 5.4.

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