The BRCA genes produce DNA repair proteins. Genetic testing is available that can determine if a person has a mutation in the BRCA genes that makes the proteins less able to function. What is the result of a BRCA mutation? O A. The person is more likely to develop cancer if other DNA in the cell mutates. O B. The person is less likely to develop cancer unless the BRCA region is methylated. O C. The person is less likely to develop cancer because the BCA gene will inhibit the cell cycle checkpoints. O D. The person is more likely to develop cancer because the BRCA gene promotes an increased rate for mitosis.

The BRCA genes produce DNA repair proteins. Genetic testing is available that can determine if a person has a mutation in the BRCA genes that makes the proteins less able to function. What is the result of a BRCA mutation? O A. The person is more likely to develop cancer if other DNA in the cell mutates. O B. The person is less likely to develop cancer unless the BRCA region is methylated. O C. The person is less likely to develop cancer because the BCA gene will inhibit the cell cycle checkpoints. O D. The person is more likely to develop cancer because the BRCA gene promotes an increased rate for mitosis.

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter22: Genes And Disease: Cancer

Section: Chapter Questions

Problem 1CT

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Similar questions

A. Which genes could be used to monitor the process of the disease? B. If you worked for a drug company developing a treatment for the cancer, which genes would you target to turn on in cancer cells? C. Which genes would you target to turn off in cancer cells?
Which of the following types of mutations are advantageous to cancer cell growth? a. Those resulting in defective mismatch repair b. Inherited defects in double-strand DNA repair c. A defect in nucleotide-excision repair d. A, B, and C e. None of the above
True or False: Cancers develop when many mutations develop rather than from a single mutation
What might best explain why the incidence of cancer increases as people age? Select one: a. mutations accumulate as people age b. cell division increases as people age c. protein synthesis increases as people age d. telomerase activity increases as people age e. ATP production increases as people age
A subset of colorectal cancers is associated with mutations in the Mut genes which code for proteins involved in repairing DNA mismatches. How would mutations in the Mut genes affect the DNA of an individual?
Gene expression array technology has been used to do which of the following (select all that apply)? A. Determine liklihood of metastasis B. Determine the most relevant treatment for individual patients based on their genomic “signature.” C. Determine therapeutic index of cancer drug D. Predict the likelihood of disease recurrence in individuals based on gene expression signatures E. Stratify patients with breast cancer into groups predictive of response to therapy
Which statement about transposons is INCORRECT? a.A transposon is a small fragment of DNA that can move from one location in a chromosome to another location in the same chromosome. b.Transposon insertion into a gene causes a mutation that can be reversed by removal of the transposon. c.Transposon movement often occurs when the cell is under genomic stress. d.In nature, insertion of a transposon can be deliberately added into a harmful gene to enhance survival.
(a) How does the duplication of individual genes occur? (b) individual that inherit a genetic condition known as xeroderma pigmentosum exhibit an extreme sensitivity to sunlight exposure and often develop skin cancer by the age of 10. What repair pathway is most likely disrupted as a result of such mutation? Explain why?
In cancer like disease, what kind of mutations are more focussed? Single Nucleotide Polymorphism or multiple mutations that occur in same gene?
What separates cancer cells from normal cells? Describe one form of mutation that can increase the risk of a normal cell being cancerous.
Which of the following effectively describes the situation of someone with an inherited predisposition to cancer such as familial adenomatous polyposis or BRCA-associated familial breast cancer? Choose all that apply a) If they get malignant cancer, somatic mutations will not have been a factor b) Their cancer will most likely arise in their germ cells, not their somatic cells c) None of the answers effectively describes the situation d) Every cell of their body contains a gain-of-function allele of an oncogene e) Most cells in their body contain multiple cancer-causing mutations f) Every cell of their body contains a defective, loss-of-function allele of a tumor suppressor gene
Draw a diagram of how we can treatment the Cancer by using gene therapy? Please draw at your own hands.