The image below shows the citric acid cycle. Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction Acetyl-CoA Condensation CH₂-C-S-CoA H₂O

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter28: Specific Catabolic Pathways: Carbohydrate, Lipid, And Protein Metabolism
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Problem 28.81P
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Chemistry
the image below shows the citric acid cycle.
The image below shows the citric acid cycle.
Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction
Acetyl-CoA
Condensation
CH₂-C-S-CoA H₂O
CoA-SH
citrate
CH₂-COO™
synthase
011000
HO-C-COO™
(2a
CH₂-COO Dehydration
Dehydrogenation
Citrate
Citric acid
H₂O
aconitase
cycle
NADH
malate
Coo- dehydro-
genase
HO-CH
Malate
COO™
Hydration fumarase
H₂O
COO™
Fumarate CH
HC
coo
Dehydrogenation
CH₂
CH₂-COO
Oxaloacetate
FADH₂
succinate
dehydrogenase
CH₂-COO
CH₂
COO-
Succinate
succinyl-CoA
synthetase
Succinyl-CoA
CH-COO™
c-coo
c-c0011
aconitase
CO₂
cis-Aconitate
H₂O
(2b
Hydration
Isocitrate
Oxidative
decarboxylation
a-ketoglutarate
dehydrogenase
complex
CH₂-COO™
COA-SH
CH₂
CoA-SH
GTP
GDP C-5-CoA
(ATP)
(ADP)
+ P₁
Substrate-level
Oxidative
decarboxylation
phosphorylation
Figure 16-7
Lehninger Principles of Biochemistry, Fifth Edition
2008 W.H. Freeman and Company
O The reaction is NADH dependent
O A phosphate group is taken from the Coenzyme A substrate
O The reaction is part of 'acetyl-CoA catabolism' phase 1.
O The reaction is part of 'regeneration of oxaloacetate' phase 2.
O The reaction is a more efficient source of ATP compared to oxidative phosphorylation.
CH₂-COO™
H-C-COO™
HO-CH
isocitrate
dehydrogenase Coo
CO₂
CH₂-COO
CH₂
-a-ketoglutarate
COO™
Transcribed Image Text:Chemistry the image below shows the citric acid cycle. The image below shows the citric acid cycle. Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction Acetyl-CoA Condensation CH₂-C-S-CoA H₂O CoA-SH citrate CH₂-COO™ synthase 011000 HO-C-COO™ (2a CH₂-COO Dehydration Dehydrogenation Citrate Citric acid H₂O aconitase cycle NADH malate Coo- dehydro- genase HO-CH Malate COO™ Hydration fumarase H₂O COO™ Fumarate CH HC coo Dehydrogenation CH₂ CH₂-COO Oxaloacetate FADH₂ succinate dehydrogenase CH₂-COO CH₂ COO- Succinate succinyl-CoA synthetase Succinyl-CoA CH-COO™ c-coo c-c0011 aconitase CO₂ cis-Aconitate H₂O (2b Hydration Isocitrate Oxidative decarboxylation a-ketoglutarate dehydrogenase complex CH₂-COO™ COA-SH CH₂ CoA-SH GTP GDP C-5-CoA (ATP) (ADP) + P₁ Substrate-level Oxidative decarboxylation phosphorylation Figure 16-7 Lehninger Principles of Biochemistry, Fifth Edition 2008 W.H. Freeman and Company O The reaction is NADH dependent O A phosphate group is taken from the Coenzyme A substrate O The reaction is part of 'acetyl-CoA catabolism' phase 1. O The reaction is part of 'regeneration of oxaloacetate' phase 2. O The reaction is a more efficient source of ATP compared to oxidative phosphorylation. CH₂-COO™ H-C-COO™ HO-CH isocitrate dehydrogenase Coo CO₂ CH₂-COO CH₂ -a-ketoglutarate COO™
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