The male is heterozygous for Huntington’s disease and homozygous dominant for Tay-Sachs. The female is homozygous recessive for Huntington’s disease and heterozygous for Tay-Sachs

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
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Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 21QP: Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic...
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young couple is planning to have children. The male is heterozygous for Huntington’s disease and homozygous dominant for Tay-Sachs. The female is homozygous recessive for Huntington’s disease and heterozygous for Tay-Sachs. The couple is curious about the possibility and probability of their offspring inheriting Tay-Sachs and/or Huntington’s. For humans, Huntington’s disease is dominant (H) over the “normal” condition (h), and the “normal” condition is dominant (T) over Tay-Sachs (t). Complete a Punnett square for this cross and record the percent probabilities for genotypes and phenotypes of the offspring.
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