The most common method for the synthesis of unsymmetrical ethers is the Williamson synthesis, a reaction (SN2) of an alkoxide ion with an alkyl halide. Two pathways are possible, but often one is preferred. Construct the preferred pathway for the synthesis of 2-propoxypropane from propene, with propene-derived alkyl halide and alkoxide intermediates, by dragging the appropriate intermediates and reagents into their bins. Not every given reagent or intermediate will be used HBr но Br CH2CI2 Step 1 Product BзН6 H2O2 Reagent 1 Br Na Но propene Reagent 2 Reagent 3 Nat о. H20 Step 2 Product Step 3 Product H2SO4 HBr ROOR + - NaBr NaH 2-propoxypropane

The most common method for the synthesis of unsymmetrical ethers is the Williamson synthesis, a reaction (SN2) of an alkoxide ion with an alkyl halide. Two pathways are possible, but often one is preferred. Construct the preferred pathway for the synthesis of 2-propoxypropane from propene, with propene-derived alkyl halide and alkoxide intermediates, by dragging the appropriate intermediates and reagents into their bins. Not every given reagent or intermediate will be used HBr но Br CH2CI2 Step 1 Product BзН6 H2O2 Reagent 1 Br Na Но propene Reagent 2 Reagent 3 Nat о. H20 Step 2 Product Step 3 Product H2SO4 HBr ROOR + - NaBr NaH 2-propoxypropane

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter9: Nucleophilic Substitution And Β-elimination

Section: Chapter Questions

Problem 9.48P: The Williamson ether synthesis involves treatment of a haloalkane with a metal alkoxide. Following...

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