Answered: The –NHCOR group of an amide is an…

The –NHCOR group of an amide is an activating group, but it is not as strongly activating as NH2. (a) Explain why it is an activating group. (b) Explain why it is less activating than NH2.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter27: Amines

Section: Chapter Questions

Problem 2E

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Question

The –NHCOR group of an amide is an activating group, but it is not as strongly activating as NH₂.

(a) Explain why it is an activating group.

(b) Explain why it is less activating than NH₂.

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