The normal pH of blood is 7.40 6 0.05 and is controlled in part by the H2CO3/HCO3- buffer system.(a) Assuming that the Ka value for carbonic acid at 25oC applies to blood, what is the [H2CO3]/[HCO3-] ratio in normal blood?(b) In a condition called acidosis, the blood is too acidic. What is the [H2CO3]/[HCO3-] ratio in a patient whose blood pH is 7.20?

Given: The pH of the blood= 7.20 The Ka for the carbonic acid=4.5 * 10-7.

Answered: The normal pH of blood is 7.40 6 0.05…

Principles of Modern Chemistry

8th Edition

ISBN:9781305079113

Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler

Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler

Chapter15: Acid–base Equilibria

Section: Chapter Questions

Problem 49P

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The normal pH of blood is 7.40 6 0.05 and is controlled in
part by the H₂CO₃/HCO₃^- buffer system.
(a) Assuming that the Ka value for carbonic acid at 25^oC applies
to blood, what is the [H₂CO₃]/[HCO₃^-] ratio in normal blood?
(b) In a condition called acidosis, the blood is too acidic. What is
the [H₂CO₃]/[HCO₃^-] ratio in a patient whose blood pH is 7.20?

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