The sequence of the start of the c-Myc gene is as follows (first picture): Use this information to answer the next five (5) questions 1.What will be the sequence of the first 5 nucleotides of the primary transcript of this gene? (Write the sequence from 5' to 3') 2. Suppose an origin of replication is at nucleotide +1, and primase adds RNA primers (only 5 nucleotides long) on the continuous strand(s). What will be the sequence(s) of this (these) primer(s)? Be sure to note the 5' - 3' orientation of the primer(s). (6 response items) 3. What will be the first 2 amino acids encoded by this mRNA? (A table of codons is provided for you to see second picture)

Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
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The sequence of the start of the c-Myc gene is as follows (first picture): Use this information to answer the next five (5) questions

1.What will be the sequence of the first 5 nucleotides of the primary transcript of this gene? (Write the sequence from 5' to 3')

2. Suppose an origin of replication is at nucleotide +1, and primase adds RNA primers (only 5 nucleotides long) on the continuous strand(s). What will be the sequence(s) of this (these) primer(s)? Be sure to note the 5' - 3' orientation of the primer(s). (6 response items)

3. What will be the first 2 amino acids encoded by this mRNA? (A table of codons is provided for you to see second picture)

4. The c-myc gene has several exons. What are the stages of the maturation process that its main transcript must undergo before becoming a mature mRNA

+1
5' CGTACCATGGTAACGTGGTACCCATGCAGTCA 3'
3' GCATGGTACCATTGCACCATGGGTACGTCAGT 5'
Transcribed Image Text:+1 5' CGTACCATGGTAACGTGGTACCCATGCAGTCA 3' 3' GCATGGTACCATTGCACCATGGGTACGTCAGT 5'
le code génétique
Deuxième lettre
C
A
Phe UCU Ser UAU Tyr
Phe UCC Ser UAC Tyr
Leu UCA Ser UAA Stop UGA Stop A
Leu UCG Ser UAG Stop UGG Trp G
UGU Cys U
UGC Cys C
UUU
UUC
U
UUG
UUA
Leu CCU Pro CAU His CGU Arg U
CUU
CỤC Leu CCC Pro CAC His CGC Arg c
CUA
CUG Leu
Leu CCA Pro CAA Gln CGA Arg A
CCG Pro CAG Gln | CGG Arg G
AUU Ile ACU Thr AAU Asn
AUC Ile ACC Thr AAC Asn
AUA Ile ACA Thr AAA Lys
AUG Met ACG Thr AAG Lys
AGU Ser U
AGC Ser C
AGA Arg A
AGG Arg G
Val
GCU Ala GAU Asp | GGU Gly U
GUU
GUC Val
G GUA Val GCA Ala GAA Glu GGA Gly A
GUG
GCC Ala GAC Asp GGC Gly C
Val GCG Ala GAG Glu GGG Gly G
codon d'initiation
codon de terminaison
Première lettre (côté 5')
Troisième lettre (côté 3')
Transcribed Image Text:le code génétique Deuxième lettre C A Phe UCU Ser UAU Tyr Phe UCC Ser UAC Tyr Leu UCA Ser UAA Stop UGA Stop A Leu UCG Ser UAG Stop UGG Trp G UGU Cys U UGC Cys C UUU UUC U UUG UUA Leu CCU Pro CAU His CGU Arg U CUU CỤC Leu CCC Pro CAC His CGC Arg c CUA CUG Leu Leu CCA Pro CAA Gln CGA Arg A CCG Pro CAG Gln | CGG Arg G AUU Ile ACU Thr AAU Asn AUC Ile ACC Thr AAC Asn AUA Ile ACA Thr AAA Lys AUG Met ACG Thr AAG Lys AGU Ser U AGC Ser C AGA Arg A AGG Arg G Val GCU Ala GAU Asp | GGU Gly U GUU GUC Val G GUA Val GCA Ala GAA Glu GGA Gly A GUG GCC Ala GAC Asp GGC Gly C Val GCG Ala GAG Glu GGG Gly G codon d'initiation codon de terminaison Première lettre (côté 5') Troisième lettre (côté 3')
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