Through GWAS explorations, scientists have identified several SNPs linked to obesity in people who livein the United States. One of these SNPs was within agene called FTO. Interestingly, a common FTO variant is associated with obesity, but only in people bornafter 1945. Moreover, the later the birth year, thehigher the risk for obesity associated with this variantof FTO. Why would a genetic risk factor for obesityvary by birth year?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Through GWAS explorations, scientists have identified several SNPs linked to obesity in people who live
in the United States. One of these SNPs was within a
gene called FTO. Interestingly, a common FTO variant is associated with obesity, but only in people born
after 1945. Moreover, the later the birth year, the
higher the risk for obesity associated with this variant
of FTO. Why would a genetic risk factor for obesity
vary by birth year?

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