From gene expression studies on development of the gut, you have decided to study a gene called Ulcer1. This gene is over expressed in people when they develop ulcers, but the cell types responsible for formation of ulcers are not known and if Ulcer1 is directly responsible for ulcer formation is not known. Results of a gene knock out of Ulcer1 in mice that was performed by another laboratory, revealed that conventional knock out of Ulcer1 is lethal shortly after birth. b. Describe an approach for determining which cell types express Ulcer1 using a transgenic approach with a reporter gene. Include a description of all elements of the vector that you will need

From gene expression studies on development of the gut, you have decided to study a gene called Ulcer1. This gene is over expressed in people when they develop ulcers, but the cell types responsible for formation of ulcers are not known and if Ulcer1 is directly responsible for ulcer formation is not known. Results of a gene knock out of Ulcer1 in mice that was performed by another laboratory, revealed that conventional knock out of Ulcer1 is lethal shortly after birth. b. Describe an approach for determining which cell types express Ulcer1 using a transgenic approach with a reporter gene. Include a description of all elements of the vector that you will need

Biology Today and Tomorrow without Physiology (MindTap Course List)

5th Edition

ISBN:9781305117396

Author:Cecie Starr, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Christine Evers, Lisa Starr

Chapter10: Biotechnology

Section: Chapter Questions

Problem 4DID

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