Trait Allele Effect CH CW Feather colour Produces black feathers in homozygotes Produces white feathers in homozygotes Produces straight feathers in homozygotes Produces frizzled feathers in homozygotes Feather shape S
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- Two alleles at one locus produce three distinctphenotypes. Two alleles of two genes lead tofive distinct phenotypes. Two alleles of six geneslead to 13 distinct phenotypes. (These statementsassume that the alleles at any one locus arecodominant or incompletely dominant andthat each gene makes an equal contributionto the phenotype.)a. Derive a formula to express this relationship. (Letn equal the number of genes.)b. Each of the most extreme phenotypes for a traitdetermined by two alleles at one locus are foundin a proportion of 1/4 in the F2 generation. If twoalleles of two genes determine the trait, each extreme phenotype will be present in the F2 as 1/16of the population.In common wheat (Triticum aestivum),kernel color varies from red to white andthe genes controlling the color act additively,that is, alleles for each gene are incompletelydominant and each gene contributes equallyto the color. A true-breeding red variety iscrossed to a true-breeding white variety, and1/256 of the F2…In domestic chicken, feather colour and shape are two traits which are controlled by autosomal alleles that are co-dominant. Table 2 shows the alleles and phenotype of both traits. The heterozygous state for feather colour is grey while the heterozygous state for feather shape is mildly frizzled. TABLE 2 Trait Allele Effect Feather colour CB Produces black feathers in homozygotes CW Produces white feathers in homozygotes Feather shape SS Produces straight feathers in homozygotes SF Produces frizzled feathers in homozygotes (a)A farmer bred a black frizzled rooster with a grey mildly frizzled hen. Draw a genetic diagram to show the expected results of this cross. Include in your answer the phenotypic ratios. (b)Is it necessary to do a test cross to determine the genotypes of the offspring? Explain your answer. (c)The farmer would like all his chickens grey and mildly…In rabbits, black color (B) is dominant to brown (b), while fullcolor (C) is dominant to chinchilla (c ch). The genes controllingthese traits are linked. Rabbits that are heterozygous for bothtraits and express black, full color are crossed to rabbits thatexpress brown, chinchilla with the following results:31 brown, chinchilla 34 black, full16 brown, full 19 black, chinchillaDetermine the arrangement of alleles in the heterozygousparents and the map distance between the two genes.
- In Drosophila, the autosomal recessive dp allele ofthe dumpy gene produces short, curved wings, whilethe autosomal recessive allele bw of the brown genecauses brown eyes. In a testcross using femalesheterozygous for both of these genes, the followingresults were obtained:wild-type wings, wild-type eyes 178wild-type wings, brown eyes 185dumpy wings, wild-type eyes 172dumpy wings, brown eyes 181In a testcross using males heterozygous for both ofthese genes, a different set of results was obtained:wild-type wings, wild-type eyes 247dumpy wings, brown eyes 242a. What can you conclude from the first testcross?b. What can you conclude from the second testcross?c. How can you reconcile the data shown in parts (a)and (b)? Can you exploit the difference betweenthese two sets of data to devise a general test forsynteny in Drosophila?d. The genetic distance between dumpy and brown is91.5 m.u. How could this value be measured?Figure 19-11 shows the expected distributions for thethree genotypic classes if the B locus is a QTL affectingthe trait value.a. As drawn, what is the dominance/additive (D/A)ratio?b. How would you redraw this figure if the B locus hadno effect on the trait value?c. How would the positions along the x-axis of thecurves for the different genotypic classes of the B locuschange if D/A = 1.0?Labrador retrievers may be black, brown, or golden in color (seethe chapter opening photograph on p. 53). Although each colormay breed true, many different outcomes occur if numerous littersare examined from a variety of matings, where the parentsare not necessarily true-breeding. The following results showsome of the possibilities. Propose a mode of inheritance that isconsistent with these data, and indicate the corresponding genotypesof the parents in each mating. Indicate as well the genotypesof dogs that breed true for each color.(a) black * brown ¡ all black(b) black * brown ¡ 1/2 black1/2 brown(c) black * brown ¡ 3/4 black1/4 golden(d) black * golden ¡ all black(e) black * golden ¡ 4/8 golden3/8 black1/8 brown(f) black * golden ¡ 2/4 golden1/4 black1/4 brown(g) brown * brown ¡ 3/4 brown1/4 golden(h) black * black ¡ 9/16 black4/16 golden3/16 brown
- A wild-type fruit fly (heterozygous for gray body color andnormal wings) is mated with a black fly with vestigial wings.The offspring have the following phenotypic distribution: wildtype, 778; black vestigial, 785; black normal, 158; gray vestigial,162. What is the recombination frequency between these genesfor body color and wing size? Is this consistent with the resultsof the experiment in Figure 15.9?Assume that plant height is determined by a pair of alleles at each of two loci (A and a, B and b) that are additive in their effects. Further assume that each allele represented by an uppercase letter contributes 6 feet to height and that each allele represented by a lowercase letter contributes 2 foot to height. If a plant with genotype Aabb is crossed to a plant with genotype aaBb, what heights are expected in the progeny? 1/216ft : 1/2 12ft 1/4 16ft : 1/2 12ft : 1/4 8ft 1/4 20ft : 1/2 16ft : 1/4 12ft 1/4 24ft : 1/2 20ft : 1/4 16ft 1/2 20ft : 1/2 16ftIn rabbits, the color of body fat is controlled by a single genewith two alleles, designated Y and y. The outcome of this traitis affected by the diet of the rabbit. When raised on a standardvegetarian diet, the dominant Y allele confers white body fat,and the y allele confers yellow body fat. However, when raisedon a xanthophyll-free diet, a homozygote yy rabbit has whitebody fat. If a heterozygous rabbit is crossed to a rabbit withyellow body fat, what are the proportions of offspring withwhite and yellow body fat when raised on a standard vegetariandiet? How do the proportions change if the offspring are raisedon a xanthophyll-free diet?
- When many families were tested for the ability to tastethe chemical phenylthiocarbamide, the matings weregrouped into three types and the progeny were totaled,with the results shown below:ChildrenNumber NonParents of families Tasters tastersTaster × taster 425 929 130Taster × nontaster 289 483 278Nontaster × nontaster 86 5 218With the assumption that PTC tasting is dominant (P)and nontasting is recessive (p), how can the progenyratios in each of the three types of mating be accountedfor?Total fingerprint ridge count exemplifies a polygenic inheritance pattern. Penrose (1969) and others have suggested that a minimum of seven gene loci contribute to TRC, but a four-locus model is hypothesized in the problems that follow. Thus, AABBCCDD represents the genotype for maximum ridge count and aabbccdd symbolizes the genotype for the minimum ridge count. Assume that each active allele adds 15 ridges to the TRC of the male and 12 to the TRC of the female and that having the genotype aabbccdd produces a baseline TRC of 70 for males and 50 for females. Predict the TRC for each of the following individuals: Genotype Male Female AABBCCDD AabbccDd AaBBCcDD aaBbCCDd A. Write the genotypes of parents who are heterozygous for all four genes. B. Write the genotype of their child who has the maximum number of active alleles possible. C. What are the TRCs for the parents? D. What is the TRC of the child from B (assume male)?…Total fingerprint ridge count exemplifies a polygenic inheritance pattern. Penrose (1969) and others have suggested that a minimum of seven gene loci contribute to TRC, but a four-locus model is hypothesized in the problems that follow. Thus, AABBCCDD represents the genotype for maximum ridge count and aabbccdd symbolizes the genotype for the minimum ridge count. Assume that each active allele adds 15 ridges to the TRC of the male and 12 to the TRC of the female and that having the genotype aabbccdd produces a baseline TRC of 70 for males and 50 for females. Predict the TRC for each of the following individuals: Genotype Male Female AABBCCDD AabbccDd AaBBCcDD aaBbCCDd