Progeny phenotypes dt D+ Cross ở Trf-ab Trf-b Trf-ab Trf-b Total d* Trf" d Trf d Trfb 32 3 21 62 d Trft d Trf" d Trfb dt Trf" 16 38 d Trfb d* Trf" 3 d Trfh 35 9. 4 30 78 d Trf d Trf d Trf d Trf d* Trf" 21 3 2 19 45 d Trf d' Trf d Trf" d Trf d Trf d* Trf" d Trf" 29 22 64 d Trft 6. d Trf 4 14 11 0 29 20 Transferrin is a blood protein that is encoded by the transferrin locus (Trf). In house mice, the two alleles at this locus (Trf and TrP) are codominant and encode three types of transferrin: Genotype Phenotype Trf / Trf Trf / TrP Trp / Trp Trf-a Trf-ab Trf-b The dilution locus, found on the same chromosome, determines whether the color of a mouse is diluted or full; an allele for dilution (d) is recessive to an allele for full color (d"): Genotype Phenotype d* d* d* (full color) d* (full color) d* d dd d (dilution) Donald Shreffler conducted a series of crosses to determine the map distance between the transferrin locus and the dilution locus (D. C. Shreffler. 1963. Journal of Heredity 54:127-129). The following table presents a series of crosses carried out by Shreffler and the progeny resulting from these crosses.

Progeny phenotypes dt D+ Cross ở Trf-ab Trf-b Trf-ab Trf-b Total d* Trf" d Trf d Trfb 32 3 21 62 d Trft d Trf" d Trfb dt Trf" 16 38 d Trfb d* Trf" 3 d Trfh 35 9. 4 30 78 d Trf d Trf d Trf d Trf d* Trf" 21 3 2 19 45 d Trf d' Trf d Trf" d Trf d Trf d* Trf" d Trf" 29 22 64 d Trft 6. d Trf 4 14 11 0 29 20 Transferrin is a blood protein that is encoded by the transferrin locus (Trf). In house mice, the two alleles at this locus (Trf and TrP) are codominant and encode three types of transferrin: Genotype Phenotype Trf / Trf Trf / TrP Trp / Trp Trf-a Trf-ab Trf-b The dilution locus, found on the same chromosome, determines whether the color of a mouse is diluted or full; an allele for dilution (d) is recessive to an allele for full color (d"): Genotype Phenotype d* d* d* (full color) d* (full color) d* d dd d (dilution) Donald Shreffler conducted a series of crosses to determine the map distance between the transferrin locus and the dilution locus (D. C. Shreffler. 1963. Journal of Heredity 54:127-129). The following table presents a series of crosses carried out by Shreffler and the progeny resulting from these crosses.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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In Drosophila, three autosomal genes have the following map:20 m.u. 10 m.u.a b ca. Provide the data, in terms of the expected numberof flies in the following phenotypic classes, whena+ b+ c+/ a b c females are crossed to a b c / a b c males. Assume 1000 flies are counted and that nointerference exists in this region.a+ b+ c+a b ca+ b ca b+ c+a+ b+ ca b c+a+ b c+a b+ cb. If the cross was reversed, such that a+ b+ c+ / a b cmales are crossed to a b c / a b c females, howmany flies would you expect in the same phenotypic classes?
From a Drosophila testcross, the number of each phenotype obtained was as follows: W+ m f+ 218 W m+ f 236 W+ m+ f 168 W m f+ 178 W+ m f 95 W m+ f+ 101 W+ m+ f+ 3 W m f 1 Total, 1000 Construct a genetic map.
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