Two drugs have a selectivity factor a = 1.08 and capacity factors k, = 5.0 and k₂= 5.4. If the plate height is 0.20 mm, how long must the column be for a resolution of 1.5? Hide answer choices A 17.3 m B 22.3 m C) 87.4 m 34.5 m Correct answer

Two drugs have a selectivity factor a = 1.08 and capacity factors k, = 5.0 and k₂= 5.4. If the plate height is 0.20 mm, how long must the column be for a resolution of 1.5? Hide answer choices A 17.3 m B 22.3 m C) 87.4 m 34.5 m Correct answer

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter34: Particle Size Determination

Section: Chapter Questions

Problem 34.13QAP

See similar textbooks

Related questions

Q: + What quantity in moles of CH₂NH₂Cl need to be added to 200.0 mL of a 0.500 M solution of CH₂NH₂…

Q: Part A To what volume should you dilute 120 mL of an 7.95 M CuCl₂ solution so that 52.0 mL of the…

Q: Ag In this reaction, how many grams of Ag will be produced if 2.28 moles of Cu(NO3), are also…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: A student prepares a 0.41 mM aqueous solution of acetic acid (CH₂co₂H). Calculate the fraction of…

Q: Macmillan Learning Translate the given conformer from the wedge-and-dash drawing into its Newman…

A: A Newman projection is a convenient way of sighting down a particular carbon carbon bond. In a…

Q: A crucible weighs 25.45 g. A crucible and antimony weighs 28.45 g. After reacting with sulfur, a…

A: Weight of crucible = 25.45 gm = aWeight of crucible and antimony= 28.45 gm = bWeight of crucible +…

Q: is a melting point alone sufficient to idenitfy a compound? why or why not?

A: The question is based on the concept of experimental Chemistry.We need to explain the significance…

Q: Calculate the pH of the solution that results from mixing 61.0 mL of 0.062 MHCN(aq) with 39.0 mL of…

A: we have to calculate the pH of the solution using the given values

Q: The preparations of two aqueous solutions are described in the table below. For each solution, write…

A: In these question acid or base has been added into a solution and we have to find out the reaction…

Q: What is the relationship between the structure of a molecule and its reactivity, and how does it…

A: The relationship between the structure of a molecule and its reactivity is a fundamental concept in…

Q: 6. When 1.464 g of propane (C₂H₂(g)) are burned in an excess of oxygen at 1 bar and 298.15 K, 67.9…

Q: Suppose the calorimeter used for the experiment has been made of a heat-conducting material (such as…

A: A calorimeter is a device used to measure the heat exchanged during a physical or chemical process.…

Q: Oxidative cleavage of the following molecule results in two organic molecules What is the other one?…

A: The reagent NaIO4 is selective oxidizing agent for 1,2-diols to corresponding cabonyl compounds are…

Q: I need help with question 80?

A: Entropy of a reaction is defined as the increase in degree of randomness of product molecules…

Q: An electrochemical cell is constructed such that on one side a pure Zn electrode is in contact with…

A: The electrode which has a higher reduction potential has a greater tendency to gain electrons and it…

Q: Consider the two sets of Newman projections for 2,3-dibromobutane. Br H OOC HC CH, A (R, R)…

A: Given the structures of Newman projections of 2,3-Dibromobutane. Based on relation between…

Q: 64. An electrochemical cell consists of a chromium electrode in 1.0 mol/L solution of Cr(NO3)3…

A: Given spontaneous cell reaction:-Cr(s) + 3Ag+(aq) -------> Cr3+(aq) + 3Ag(s)Here, Cr undergoes…

Q: 15. Calculate the Kf of the [Fe(SCN)]2+ solution if 4 mL of 0.004M FENO3 is mixed with 6 mL of 0.004…

A: To calculate the formation constant (Kf) of the [Fe(SCN)] complex, we need to use the equation for…

Q: The student titrated 50.0 mL of 0.100 M HC2H3O2 with 0.100 M NaOH (aq). Calculate the pH of the…

A: pH of solution at equivalence point is 8.87.

Q: A certain substance X has a normal freezing point of 1.5 °C and a molal freezing point depression…

Q: What is the pH of a 0.02 M acetic acid solution?

Q: The rate of formation of ammonia in the reaction N2 (g) + H2 (g) → NH3 Is reported to be 1.15 mol…

A: N2(g) + H2(g) ----> NH3(g)Rate of formation of ammonia = d[NH3]/dt = 1.15 mol.L-1.s-1Rate of…

Q: 2. a) An isomer is: same chemical formula but different structural arrangements same structural…

A: If the compounds have the same molecular formula but have a different bonding arrangement /…

Q: 9. To prepare a 50 ml portion of 0.002M Na+ solution from a 0.01M what volume we need to take from…

A: Since you have posted multiple questions, we will provide the solution only to the first question as…

Q: 60. An electrochemical cell involves the following half-reactions: E = +0.80 V Ag+ (aq) + e² → 2+…

A: E°Ag+/Ag = +0.80 VE°Sn2+/Sn = -0.14 V

Q: 5. Rank the following compounds in order from most stable to least stable. Explain your ranking. A.…

Q: 12. Given that nickel hydroxide, Ni(OH)2, has a Ksp = 1.6×10-10, what is its molar solubility?…

A: Ksp = 1.6 × 10-16Given compound = Ni(OH)2

Q: Balanced chemical equation 2C8H18(g)+25O2(g)→16CO2(g)+18H2O(g) After the reaction, how much octane…

A: To determine how much octane is left after the reaction, we need to compare the stoichiometry of the…

Q: Octane (C8H₁8) has a vapor pressure of 14.3 torr and a density of 0.703 g/mL. Benzene (CH) has a…

A: The question is based on the concept of solutions. we need to calculate vapour pressure of the…

Q: On your own paper, balance the following redox equations using the oxidation number change method.…

A: 1) NH3 + O2 → NO2 + H2OStep 1: Assign oxidation numbers to all the elements in the equation.NH3: N…

Q: What is the concentration of A after 47.7 minutes for the reaction A -> Products when the initial…

A: Recall the given reaction, The initial concentration of A =…

Q: Using the periodic table determine how many electrons selenium needs to gain to obtain a noble gas…

Q: What is the pH of a 0.02 M HCl solution?

Q: Problems to solve pH = pka + log [A] [HA] 1. The pKa of acetic acid is 4.8. If you mix 100 ml of 0.1…

A: Using Henderson hasselbalch equation we can figure out the pH of resulting solution as well as the…

Q: 1) 2) [References] pecify the formal charges (both sign and magnitude) on the atoms labeled a-c. 26…

A: Formal charge = Number of valence electrons in neutral atom - (number of covalent bonds + number of…

Q: . Furnaces in residential homes usually burn natural gas, which is mostly methane, CH. Here is the…

A: Concept: The answer emphasizes the importance of servicing furnaces before winter due to the…

Q: A sample of an unknown hydrated compound weighed 16.450 grams. After heating, it had a mass of…

A: Given: Mass of hydrated compound = 16.450 gmass of anhydrated compound=10.319 g

Q: Consider compounds 1 and 2 in the image and select the correct statement. N N. N 1 ZI ΖΙ N. aso N 2…

A: TPSA stands for Topological Polar Surface Area. It is a measure of the ability of a molecule to…

Q: Give the major product of this reaction sequence. 1) (CH3)2CuLi 2) weak acid (aq NH4CI) BA

A: The question is based on organic reactions. we need to identify the product formed and explain…

Q: Methyl acetate is hydrolyzed in approximately 1M HCI at 25°C. Aliquots of equal volume are removed…

Q: A chemistry graduate student is given 450. mL of a 0.20M nitrous acid (HNO.) solution. Nitrous acid…

Q: Where do you expect to find elements that are good oxidizing agents on the periodic table? Periodic…

Q: How many kinds of chemically non-equivalent hydrogens are there in each of the following compounds?…

Q: How many total atoms are there in each molecule of Sr(NO3)2*4H2O

A: Molecular formula = Sr(NO3)2*4H2O

Q: intermediate cannot be formed. OA ammomony B Enzyme OC OD COOH D COOH HO-O for this reaction…

A: A question based on reaction intermediate. 5 options are given, the most inappropriate intermediate…

Q: ener

A: Energy is not created or destroyed but it is transferable, that is it is transferred from one form…

Q: Curved arrows are used to illustrate the flow of electrons. Using the provided resonance structures,…

Q: 40Ca2+ How many protons, neutrons and electrons in this ion?

A: Given ion is 40Ca2+=> Atomic no. of Ca = 20 = Z => Mass no. of Ca= 40 = A

Q: Given the following values, determine the pH. The concentration of magate is 2.92mM and the…

A: The question is based on the concept of pH of the solution. it is defined as a negative logarithm…

Q: Give the major product of this reaction! F NH₂ F NH3 ㅅ

A: The question is based on organic reactions. we need to identify the product formed and explain…

Question

Subject:- Chemistry

Two drugs have a selectivity factor a = 1.08 and capacity factors k, = 5.0 and k₂= 5.4. If
the plate height is 0.20 mm, how long must the column be for a resolution of 1.5?
Hide answer choices
A
17.3 m
B 22.3 m
C) 87.4 m
34.5 m
Correct answer

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Basic

VIEW

Step 2: Calculation

VIEW

Step 3: Column length

VIEW

Solution

VIEW

Step by step

Solved in 4 steps with 3 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Quality Assurance and Calibration Methods

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

As part of an analytical chemistry laboratory course, a student measured the Ca2+ content in two water samples, city-supplied drinking water and well-supplied drinking water, using two different analytical methods, flame atomic absorption spectrometry (FAAS) and EDTA complexometric titration. The results of this experiment are given in the table as the mean Ca2+concentration (?¯) and standard deviation (?) in parts per million (ppm). Each sample was measured five times (n=5) by each method. Method City-Supplied Drinking Water (?¯±?x¯±s) Well-Supplied Drinking Water (?¯±?x¯±s) FAAS 57.57±0.68 ppm 64.77±0.70 ppm EDTA titration 58.32±0.96 ppm 65.62±0.97 ppm Method Comparison: For each drinking water sample (city and well), compare the Ca2+ content measured by FAAS and EDTA titration. Calculate the ? value for each sample. Do the methods produce statistically different results at the 95% confidence level when measuring the Ca2+content of the city-supplied drinking water? Do the…
A graphite furnace atomic absorption spectrophotometer (AAS) was used to determine the arsenic (As) concentrations in drinking water. A large set of blank samples yielded an average blank signal of 0.013 and a blank standard deviation of 0.0030. The following data were obtained for a calibration curve. [As] (ppm) 2.0 4.0 6.0 8.0 10.0 Absorbance 0.17 0.28 0.48 0.53 0.72 Using a spreadsheet on an Excell, create a graph of the data using symbols only for the data points. Plot the line on the same graph and include the graph to this question. (a). What is the sensitivity of the method? (b). Calculate the LOD and LOQ for As. (c). A sample of water yielded an absorbance of 0.43. What is the concentration of As in the water?
For the determination of iron in used jet engine oil, 30 analyzes with 3 repetitions each were made by atomic absorption method and the standard deviation was found s=2.4 µg Fe/mL. Since this standard deviation value is close to the ϭ value, the iron concentration of 18.5 µg Fe/mL(a) by a single analysis,(b) as the average of the two analyzes,(c) Calculate the 80% and 95% confidence intervals if found as the mean of four analyses.
Internal standard (As , Cs ), analyte with known concentration (Ax , Cx ) In a chromatographic equipment, a solution containing 0.006727 X and 0.008331 M S give peak area of Ax= 2316 and As= 207. To analyze an unknown sample, 5.0mL of 0.008331M S was added to 5.0mL of X, and the mixture was diluted to 50.0mL. This mixture gave a chromatography spectrum with area Ax= 3206 and As= 200. Find Cx.
Felodipine calcium channel blocker standard (0.251mg/ml) and felodipine sample (0.245mg/ml) solutions were prepared and injected to the HPLC. The peak area of felodipine standard is 275428 and the sample is 272982. The potency (purity) of felodipine standard is 98.9%. What is the assay percentage of felodipine? a. 102.23 b. 98.71 c. 101.07 d. 100.42
Describe the following properties of chromatogram (including formula if applicable): Bandwidth Retention Volume Capacity Factor Selectivity Factor Resolution
Which of the following statements concerning calibration curves are true? 1. A plot of signal versus analyte amount or concentration 2. Measure the response of an instrument by first measuring the response from a standard 3. Used to calibrate a measurement over an extended range. a. 1 only b. 1 an 2 only c. 1 and 3 only d. 2 and 3 only e. 1, 2, and 3
Concentration=2.5 X 10^3 μM OD400nm=0.859 1cm cuvette is used what is the extinction coefficient (μM^-1 cm^-1)
You are developing a procedure for determining traces of copper materials using a wet digestion followed by measurement by atomic absorption spectrophotometry. In order to test the validity of the method, you obtain an NIST orchard leaves standard reference material and analyze this material. Five replicas are sampled and analyzed, and the mean results are found to be 10.8 ppm with a standard deviation of plus or minus 0.7. ppm. The listed value for the standard reference is 11.7 ppm. Does your method give a statistically correct value at the 95% confidence level?
Ben ran through the experiment and found the best-fit line listed below for his standard calibration curve of absorbance vs concentration in M. y = 3214.0x + 0.0076 Ben then prepared a solution that had 5.00 mL 0.002 M iron(III) nitrate in 1 M nitric acid, 3.00 mL 0.002 M potassium thiocyanate, and 2.00 mL DI water. If the absorbance for the solution was 0.436, calculate the equilibrium concentration of iron(III) thiocyanate in the solution. Report your answer in mM with three places after the decimal.
You are provided with a stock standard with a concentration of 100 mg/L, and a solution of unknown concentration. Prepare calibration standards using a 10 mL volumetric flask and a 1 mL piston pipette, and measure on the UV/Vis spectrophotometer (400 nm). Determine the concentration of the unknown after a 1:40 dilution, and provide the concentration of the initial solution. i need to learn how to do the calculations and draw a calibration curve to find concentration of unknown sample after i find the absorbances.
A solution with 0.083 7 M X and 0.050 0 M S9 gave areas AX = 423 and AS9 = 372. Then 10.0 mL of 0.05 0 M S9 plus 10.0 mL of unknown were diluted to 25.0 mL. The chromatogram gave AX = 553 and AS9 = 286. Find [X] in the unknown.