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- What is the relationship between DM and development of Pancreatic Cancer? How can we prepare patients diagnosed with stage 4 Pancreatic CA for palliative care?Explain the importance of MSH2 and MSH6 in regards to adenocarcinoma colon cancerAccording to the American Cancer Society, colon cancer screening should begin at age 50 for people at average risk. Imagine you have a family history of colon cancer. From your research, with reasons which procedures would your physician order for you and at what age ?