Q: If the solubility of a drug is 3.8g/L and in chloroform 226g/L calculate its partition coefficient…
A:
Q: 4. At 25 °C, 1.0 g of caffeine will dissolve in 47 mL of water, in 8.1 mL of chloroform, in 86 mL of…
A: The solubility of caffeine in g/100mL in each of the solvents can be calculated as:
Q: What is the chemical shift, multiplicity, and integration?
A: NMR spectroscopy stands for Nuclear magnetic resonance spectroscopy. NMR spectroscopy is used for…
Q: What are transference numbers and how are they related to ionic mobilities?
A:
Q: Solute S has a partition coefficient of 4.0 between water (phase 1) and chloroform (phase 2) in K =…
A:
Q: The octanol-water partition coefficient can be used to determine how :
A: In this question we have to tell that the octanol water partition coefficient can be used to…
Q: The partition coefficient K for a compound between dichloromethane and water is determined to be 56…
A: We have to predict the volume of solution remaining in Water.
Q: Suppose you have 0.01moles of an organic solid in 100ml of water. The partition coefficient P…
A:
Q: c) diethyl ether. After separating the layers, 240 mg of cyclohexanol are recovered from the diethyl…
A:
Q: Let the retention factor of species A be 0.5, while the retention factor of species B be 0.3. If…
A: Given Rf = Retention factor Rf(A) = 0.5 Rf(B) = 0.3 Distance travelled by solute A = 1.0 cm
Q: How would I go about doing this?At 25 °C, the octanol-water equilibrium partition coefficient KOW of…
A: The given compound is X.The octanol – water partition coefficient is defined by,
Q: The partition coefficient of iodine between CCl4 and water is CCC14/CH20 = K = 85, where the C₁…
A:
Q: The partition coefficient for caffeine between dichloromethane and water is 4.6. Assume that a 100…
A: The partition coefficient gives the proportion of the concentration of solute dissolved in two…
Q: You add 1 mL of sample and collect 1 mL fractions from a column with a volume of 20 mL where the…
A: Ans:- Given: column size is 20ml , sample loaded is 1 ml. Now, we see that the partition coefficient…
Q: of 4.43±0. partition c
A: The urine formation as, glomerular filtration, tubular reabsorption tubular secretion
Q: At 25 °C, the octanol-water equilibrium partition coefficient KOW of Compound X is 150,000 and its…
A: Given that the first equilibrium exists between octanol and water.
Q: Explain why the partition coefficient of salicylic acid is different when a solution of 0.01 M HCl…
A: Partition coefficient are defined as the ratio of concentration of substance in organic phase with…
Q: Construct the expression for Ksp for solid Ba3(PO)2 in aqueous solution.
A:
Q: Which is referred to by the given statement ? refers to the ratio of the concentration of un-ionized…
A: Partition coefficient is defined as the ratio of the concentration of unionized species of a…
Q: (b) Explain in detail the statistical treatment of adsorption.
A: The answer is given below:
Q: Construct the expression for Ksp for solid Ba3(PO4)2 in aqueous solution. Ba3(PO.)2(s) = 3 Ba"(aq) +…
A: The expression for Ksp for solid Ba3(PO4)2 in aqueous solution has to be given.
Q: What does a partition coefficient (K) of 1.0 tell you about the solubility of a compound in water…
A: Partition coefficient(K) tells the distribution of the solute between the two immiscible solvents.…
Q: Two species A and B are known to have water/hexane partition coefficient of 5.99 and 6.16. They are…
A: Hey, since there are multiple subparts posted, we will answer first three subparts. If you want any…
Q: Solute S has a partition co-efficient of 3.0 between water (Phase 1) and Chloroform (Phase 2). (a)…
A:
Q: Naphthalene has a log Kow of 3.33. Estimate its soil-water partition coefficient normalized to…
A: For the soil-water partition coefficient normalized to organic carbon and the 95 per cent confidence…
Q: You want to decaffeinate your coffee by extracting the caffeine out with dichloromethane (they don't…
A: Dichloromethane is a very good solvent and dissolves caffeine up to a high level. So it was…
Q: What is the gravimetric factor if a weight of cl is to be determined from a weight of PbCl2?
A: A gravimetric factor converts grams of a compound into grams of a single element. Example-…
Q: 15 Asolution of butanedioic acid (BDA) in ether contains 0.034 mol of BDA in 20 cm³ of ether. This…
A: Given data = Total no of moles of BDA in ether before shaking = 0.034 mole moles of BDA in water…
Q: Mechanism of separation is partitioning
A: Ans: HILIC Hydrophilic interaction chromatography (or) hydrophilic interaction liquid…
Q: Does acetic acid associate or dissociate in water? If yes, how does it affects in determining its…
A: Yes, Acetic acid dissociates in water because it has a polar group COOH in it and hence it is a…
Q: Hi can you please help At what temperature will the vibrational partition function for I2(IODINE)…
A: The vibrational partition function is given as: qv=11-exp-hνkT (1) Where h is the Planck's…
Q: An unknown substance “A" was allowed to partition between a mixture of 150 mL water and 80 mL…
A: Partition coefficient =Concentration of A in benzeneConcentration of A in toluene…
Q: Discuss the equation for the partition coefficient and the implications of the different values for…
A: Partition coefficients help us in estimation of distribution of drugs within the body.
Q: If the solubility of a drug is 3.8 g/L and in chloroform 224.9 g/L calculate its partition…
A: Solubility of drug in water = 3.8 g/L Solubility of drug in chloroform = 224.9 g/L
Q: Ethyl heptanoate (EH), a food aroma compound, was added to water and allowed to come to equilibrium…
A: CONCEPT Partition coefficient is defined as the ratio of concentrations of a compound distributed in…
Q: When gypsum (CaSO4 2H2O) is heated to 433 K, it converts to the hemihydrate CaSO4 1 2H2O, and at…
A:
Q: Estimate the organic carbon partition coefficient Koc of benzene from (a) solubility and (b) logKow…
A: Interpretation - To estimate the organic carbon partition coefficient Koc of benzene from (a)…
Q: Simple extractions are particularly useful for separations where only one component has a favorable…
A: Several important separation techniques are based on a simple extraction, including liquid–liquid,…
Q: When a solution of 1.00 g of X in 100 cm3 of water was shaken with 10 cm³ of ether, 0.80 g of X was…
A: Answer:- This question is answered by using the simple concept of calculation of partition…
Q: The octanol - water aqueous buffer partition coefficients (P) for a drug used to treat glaucoma were…
A: The partition coefficients for a drug at various pH and water are given. We are required to find out…
Q: Iodine is being extracted from 200 mL water using 50 mL CCl4. The partition coefficient for I2 being…
A: Solvent extraction: If V mL of a solution containing W gram of solute to be repeatedly extracted…
Q: Fill in the blank. In solvent extraction, the value of partition coefficient should be ________ in…
A: Solvent extraction is performed for extraction process in which a compound transfer from one…
Q: In the water and nitrogen molecules, do they have the same electronic partition function? Explain it…
A: In molecules, generally only the ground electronic state is accessible, under a wide range of…
Q: What is the partition Coefficient of phenazopyridine? With illustration
A: partition coefficient is defined as the ratio of ionized drug distributed beween organic phase and…
Q: For a carbon granule microphone, determine a suitable value for m. if the contribution from each of…
A: Solution - According to the question - Given - For each of the higher order terms is to be less…
Q: You left a bowl of refried beans in the refrigerator too long. One day your roommate opens the…
A: Hi there! Since you have posted multiple questions, we will answer the first one for you.
Q: 10mL of an aqueous solution containing 0.020 M RCOOH (pKa = 6.00) is mixed with 10mL of CCI4. The…
A:
Q: Suppose that the acid HA (with dissociation constant Ka) is partitioned between aqueous phase 1 and…
A: Distribution coefficient: It is defined as the ratio of the total concentration in phase 2 and the…
Q: The absorbance of a 0.5 mM aqueous salicylic acid solution was 0.925. This solution was extracted…
A:
what can we discuss/say on solvent polarity with regards to partition coefficient?
Step by step
Solved in 3 steps with 1 images
- If the solubility of a drug is 3.8g/L and in chloroform 226g/L calculate its partition coefficient to 1 decimal placeAcetone has a partition coefficient of 13 while DCM has a partition coefficient of 4.6. Why is DCM used for the extraction of caffeine from Black teabags?Define a molar extinction coefficient and briefly describe how it is measured.
- Describe the physical significance of the molecular partition function .As part of a lab exercise, your group was assigned an unknown compound X for which you had to determine its partition coefficient between an organic solvent and water. You dissolve and shake 4 grams of X in a mixture of 130 mL benzene and 100 mL of water. At the end, your group discovered that the benzene layer contained 0.5 g of X. Use the information provided to calculate for the partition coefficient. What can you say about the chemical nature of compound X?What is the partition Coefficient of phenazopyridine? With illustration
- Fill in the blank. In solvent extraction, the value of partition coefficient should be ________ in order for separation to occur.If the solubility of a drug is 3.8 g/L and in chloroform 224.9 g/L calculate its partition coefficient.By what factor must the applied magnetic field be increased for the relative population difference (Nɑ - Nβ)/N to be increased by a factor of 5 for (i) 1H nuclei, (ii) 13C nuclei?
- What do you mean by the term equilibrium partition coefficient?The partition coefficient(k)of a substance between petroleum ether and water is 6. A substance of mass 12 g is dissolved in 50 mL of water. Calculate the total mass of sample that can be extracted into 40 mL of ether if the ether is used in two 20 mL portions.Naphthalene has a log Kow of 3.33. Estimate its soil-water partition coefficient normalized to organic carbon and the 95 percent confidence interval of your estimate.