What does the graph tell you about the relationship between  Mg2+  concentration and ATP hydrolysis? What is the mechanism that explains the relationship between  Mg2+  concentration and ATP hydrolysis?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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The graph shows how the free‑energy change for the hydrolysis of ATP varies as a function of  Mg2+  concentration. Note that  pMg = –log[Mg2+]. 

What does the graph tell you about the relationship between  Mg2+  concentration and ATP hydrolysis?

What is the mechanism that explains the relationship between  Mg2+  concentration and ATP hydrolysis?

The graph shows how the free-energy change for the hydrolysis of ATP varies as a function of Mg²+ concentration. Note that
pMg =- log [Mg²+].
36
8.6
8.4
35
8.2
34
8.0
33
7.8
7.6
7.4
7.2
30
1
2
4
6.
7
pMg
-AG (kJ mol-1)
31
-AG (kcal molF').
Transcribed Image Text:The graph shows how the free-energy change for the hydrolysis of ATP varies as a function of Mg²+ concentration. Note that pMg =- log [Mg²+]. 36 8.6 8.4 35 8.2 34 8.0 33 7.8 7.6 7.4 7.2 30 1 2 4 6. 7 pMg -AG (kJ mol-1) 31 -AG (kcal molF').
What does the graph tell you about the relationship between Mg²+ concentration and ATP hydrolysis?
An increase in [Mg²+] increases the entropy of ATP hydrolysis.
An increase in [Mg²+] increases the phosphoryl-transfer potential of ATP.
A decrease in [Mg²+] increases the free-energy change of ATP hydrolysis.
O A decrease in [Mg²+] increases the rate of ATP hydrolysis.
What is the mechanism that explains the relationship between Mg²+ concentration and ATP hydrolysis?
O increased stabilization due to hydration
electrostatic repulsion is reduced
resonance stabilization is increased
hydrolysis products increase system entropy
Transcribed Image Text:What does the graph tell you about the relationship between Mg²+ concentration and ATP hydrolysis? An increase in [Mg²+] increases the entropy of ATP hydrolysis. An increase in [Mg²+] increases the phosphoryl-transfer potential of ATP. A decrease in [Mg²+] increases the free-energy change of ATP hydrolysis. O A decrease in [Mg²+] increases the rate of ATP hydrolysis. What is the mechanism that explains the relationship between Mg²+ concentration and ATP hydrolysis? O increased stabilization due to hydration electrostatic repulsion is reduced resonance stabilization is increased hydrolysis products increase system entropy
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