What is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex?
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What is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex?
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- Which of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalaseWhich enzyme involved in the TCA cycle produces very similar outcomes compared to pyruvate dehydrogenase ?How similar of an effect would a mutation in pyruvate dehydrogenase have, compared to a mutation in pyruvate carboxylase that blocks its ability to be regulated by acetyl-CoA?
- Does Pyruvate Dehydrogenase Complex have coenzymes and Allosteric regulation?Which of the following cofactors is NOT used by the pyruvate dehydrogenase complex? a. NAD+ b. FAD c. tetrahydrofolate d. coenzyme AWhich of the following is a negative regulator of the pyruvate dehydrogenase complex (PDC)? 1. acetyl CoA 2. ADP 3. pyruvate 4. citrate
- What is the final (terminal) electron acceptor in the mechanism of pyruvate dehydrogenase complex (PDC)? 1. FAD 2. lipoyllysine 3. TPP 4. NADfatty acid breakdown generates a large amount of acetyl CoA. What will be the effect of fatty acid breakdown on pyruvate dehydrogenase complex activity? On glycolysis?Can you explain the difference between pyruvate carrier and pyruvate dehydrogenase complex?
- Distinguish between catalytic coenzymes and stoichiometric coenzymes in the pyruvate dehydrogenase complexWhat are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and a-ketoglutarate dehydrogenase?Which one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be metabolically irreversible? Explain.