What is the intracellular voltage for Cl- if the intracellular concentration was 5 mMand the extracellular concentration was 130 mM. Write the voltage as a number inmV inside the cell relative to that outside, eg. -72 or + 90.Question 2.What is the intracellular voltage for Ca++ if the intracellular concentration was0.0008 mM and the extracellular concentration was 0.6 mM. Write the voltage as anumber in mV inside the cell relative to that outside, eg. -72 or +90. Round to thenearest milli Volt.

The Nernst equation enables the calculation of the potential that will be established across the…

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Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter3: The Plasma Membrane And Membrane Potential

Section: Chapter Questions

Problem 2SQE: One of the important uses of the Nernst equation is in describing the flow of ions across plasma...

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Assume that in a neuron, the plasma membrane permeability values for potassium (K+), sodium (Na+), and Cl− are the following: PK = 1, PNa = 12, and PCl = 0.5. Based on physiological concentrations of K+, Na+, and Cl− (refer to the table), determine the membrane potential in this neuron.
37.Given an intracellular concentration of 120mM and an extracellular concentration of 15mM, calculate the Nernst Equilibrium Potential for K+ in mV 38 Given an intracellular concentration of 2mM and an extracellular concentration of 107mM, calculate the Nernst Equilibrium Potential for Cl- in mV 39 A cell has an actual membrane potential (Em) at rest of -75mV. The equilibrium potential for Na+ is +120mV and the equilibrium potential for K+ is -95mV. Calculate the net driving force for Na+ in mV.
The resting membrane potential of a neuron at 37°C is –60 mV (inside negative). If the freeenergy change associated with the transport of Na+ from o utside to in side is –10.0 kJ/mol, and [Na+]outside the cell is 260 mM, what is [Na+] inside the cell?gas constant R=8.315 J/mol.K; Faraday constant F=96.5 kJ/mol.volt
Calculate the free energy of transport for the movement of potassium by the sodium/potassium pump under normal physiological conditions: 4 mM serum potassium, 135 mM intracellular potassium, 37.1 °C, and resting potential -82 mV. Express your answer in kJ/mol. Show all work. Calculate the free energy of transport for the movement of potassium by the sodium/potassium pump under disturbed conditions of 2 mM serum potassium. Assume all other parameters remain the same. Express your answer in kJ/mol. Show all work. What factors could limit the continued action of the sodium/potassium pump when only 2 mM potassium is present in the blood plasma? Note that under normal physiological conditions, the cell interior contains 11 mM sodium and the blood contains 140 mM sodium.
If the equilibrium potential for K* is -90mV, and the charge inside the cell is -70mV, which direction will K move across the membrane assuming there is permeability (membrane leak channels) which allow it to pass?
What is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 23 mM at 20 ∘C ?
Calculate the equilibrium membrane potentials to be expected across a membrane at 37 °C, with a NaCl concentration of 0.10 M on the “right side” and 0.01 M on the “left side”, given the following conditions. In each case, state which side is (+) and which is (-). (a) Membrane permeable only to Na+ (b) Membrane permeable only to Cl– (c) Membrane equally permeable to both ions
The resting membrane potential of a neuron typically is 70 mV. What does this mean?
Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -60 mV? Pick one of the four tables in the included image please for your answer.
Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -20 mV?
If: membrane potential=-70mV, ENa=+60mV, and Ex=-90mV, consider which directions Na+ and K+ will leak across the membrane. If both ions are crossing the membrane, what is the most important factor in determining whether membrane potential will become more positive or more negative?
when calculating the Resting membrance potential using the goldman equation it is usally out, out , in / in, in, out. the cl- is switched so does that mean that when writing the in and out cellular concentartion should we still add negative sign in front of the value or since it is flipped we shouldnt?.

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