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- The distance between two molecular markers that are linked alongthe same chromosome can be determined by analyzing the outcomesof crosses. This can be done in humans by analyzing a family’spedigree. However, the accuracy of linkage mappingwith human pedigrees is fairly limited because the number of people in mostfamilies is relatively small. As an alternative, researchers can analyze a population of sperm, produced from a single male, and computelinkage distance in this manner. As an example, let’s suppose a maleis heterozygous for two polymorphic STSs. STS-1 exists in two sizes:234 bp and 198 bp. STS-2 also exists in two sizes: 423 bp and 322bp. A sample of sperm was collected from this man, and individualsperm were placed into 40 separate tubes. In other words, there wasone sperm in each tube. Believe it or not, PCR is sensitive enough toallow analysis of DNA in a single sperm! Into each of the 40 tubeswere added the primers that amplify STS-1 and STS-2, and then thesamples were…Mendelian GeneticsF1 Cross: Yellow, Round x Green, RoundGgWw x ggWWCharacter: Pea color & shapeUse Punnett square and fork-line method to check the F2.Show and interpret all the possible genotypes and phenotypes of the offsprings.Mendelian GeneticsF1 Cross: Tall, White, Axial x Dwarf, Violet, TerminalDdwwAA x ddWWaaCharacter: Stem height, Flower color & positionUse fork-line method to check the F2.Show and interpret all the possible genotypes and phenotypes of the offsprings.B.A.I. For A and B,1. Identify the type ofinheritance. Justifyyour answer.2. Decode the genotypesof the individuals inthe pedigree. (Useletter A forrepresentation ofalleles.)3. List down all affectedIf you cross a fruit fly with the genotype Gg, Hh, II, Jj to another fruit fly with genotype Gg, Hh, Ii, jjwhat fraction of their offspring do you expect to have genotype Gg, HH, II, jj? Show your work using individual punnett square for each trait then multiplying the fractions found through the punnett squares
- The distance between two molecular markers that are linked alongthe same chromosome can be determined by analyzing the outcomesof crosses. This can be done in humans by analyzing a family’spedigree. However, the accuracy of linkage mapping in humanpedigrees is fairly limited because the number of people in mostfamilies is relatively small. As an alternative, researchers cananalyze a population of sperm, produced from a single male, andcompute linkage distance in this manner. As an example, let’ssuppose a male is heterozygous for two polymorphic STSs. STS-1exists in two sizes: 234 bp and 198 bp. STS-2 also exists in twosizes: 423 bp and 322 bp. A sample of sperm was collected fromthis man, and individual sperm were placed into 40 separate tubes.In other words, there was one sperm in each tube. Believe it or not,PCR is sensitive enough to allow analysis of DNA in a single sperm!Into each of the 40 tubes were added the primers that amplify STS-1and STS-2, and then the samples were…In most two-factor crosses involving linked genes, we cannot tellif a double crossover between the two genes has occurred becausethe offspring will inherit the nonrecombinant pattern of alleles.How does the inability to detect double crossovers affect thecalculation of map distance? Is map distance underestimated oroverestimated because of our inability to detect double crossovers?Explain your answer.How can each of the following be used in determiningthe role of genetic and/or environmental factors inphenotypic variation in different organisms?a. genetic clonesb. human monozygotic versus dizygotic twinsc. cross-fostering
- Mendelian GeneticsF1 Cross: Yellow, Round x Green, Round GgWw x ggWWCharacter: Pea color & shapeUse Punnett square and fork-line method to check the F2.Show and interpret all the possible genotypes and phenotypes of the offsprings. Mendelian GeneticsF1 Cross: Tall, White, Axial x Dwarf, Violet, Terminal DdwwAA x ddWWaaCharacter: Stem height, Flower color & positionUse fork-line method to check the F2.Show and interpret all the possible genotypes and phenotypes of the offsprings. I. For A and B,1. Identify the type of inheritance. Justify your answer.2. Decode the genotypes of the individuals in the pedigree. (Use letter A for representation of alleles.)3. List down all affected individuals.B.A.Write the number of different kinds of phenotypes,excluding sex, you would see among a large numberof progeny from an F1 mating between individuals ofidentical genotype that are heterozygous for one ortwo genes (that is, Aa or Aa Bb) as indicated. No geneinteractions means that the phenotype determined byone gene is not influenced by the genotype of theother gene.a. One gene; A completely dominant to a.b. One gene; A and a codominant.c. One gene; A incompletely dominant to a.d. Two unlinked genes; no gene interactions; Acompletely dominant to a, and B completelydominant to b.e. Two genes, 10 m.u. apart; no gene interactions; Acompletely dominant to a, and B completely dominant to b.f. Two unlinked genes; no gene interactions; A anda codominant, and B incompletely dominant to b.g. Two genes, 10 m.u. apart; A completely dominantto a, and B completely dominant to b; and withrecessive epistasis between aa and the alleles ofgene B.h. Two unlinked duplicated genes (that is, A and Bperform…In sweet pea plant, an allele for purple flowers (P) is dominant when paired with a recessive allele for red flowers (p). An allele for long pollen grains (L) is dominant when paired with a recessive allele for round pollen grain (l). Bateson and Punnett crossed a plant having purple flowers/long pollen grains with one having white/flowers/round pollen grains. All F1 offspring had purple flowers and long pollen grains. Among the F2 generation, the researchers observed the following phenotypes: 296 purple flowers/long pollen grains 19 purple flowers/round pollen grains 27 red flowers/long pollen grains 85 red flowers/round pollen grains What is the best explanation for these results?
- As it turned out, one of the tallest Potsdam Guards had an unquenchable attraction to short women. During his tenure as guard, he had numerous clandestine affairs. In each case, children resulted. Subsequently, some of the childrenwho had no way of knowing that they were relatedmarried and had children of their own. Assume that two pairs of genes determine height. The genotype of the 7-foot-tall Potsdam Guard was A9A9B9B9, and the genotype of all of his 5-foot clandestine lovers was AABB. An A9 or B9 allele in the offspring each adds 6 inches to the base height of 5 feet conferred by the AABB genotype. a. What were the genotypes and phenotypes of all the F1 children? b. Diagram the cross between the F1 offspring, and give all possible genotypes and phenotypes of the F2 progenyThe question should be whether you reject or do not reject the Fisher test null hypothesis using data for all three institutions, not for two. Test that Mode ofInheritance is Autosomal Recessive forexperiments at each of three researchinstitutions At two research instructions, the parental cross is a affected(disease) male with an unaffected (wild‐type) female. Thecross of a male and female in the F 1generation produces thefollowing counts in the F 2generation: Question to be answered: Computethe Fisher Combined P‐value test using the data fromthe two sites, and draw a conclusion (reject, do notreject) the null hypothesis for the Fisher test, namelythat the specified MOI at each site is correct. https://onlinelibrary.wiley.com/doi/10.1002/aff2.68(only abstract) https://bigislandnow.com/2022/10/23/native-predatory-fish-help-control-invasive-species-in-hawaiian-fishpond-on-o%CA%BBahu/#:~:text=Jacks%20and%20barracuda%20in%20He%CA%BBeia,on%20the%20invasive%20mullet%20species.A sex-influenced trait is dominant in males and causes bushy tails.The same trait is recessive in females. Fur color is not sex influenced.Yellow fur is dominant to white fur. A true-breeding femalewith a bushy tail and yellow fur was crossed to a white male withouta bushy tail (i.e., a normal tail). The F1 females were thencrossed to white males without bushy tails. The following resultswere obtained:A. Conduct a chi square analysis to determine if these two genesare linked.B. If the genes are linked, calculate the map distance betweenthem. Explain which data you used in your calculation.