When alanine undergoes transamination with oxaloacetate, alanine is first converted to alpha-keto acid. The enzyme uses PLP as a cofactor. Suggest a mechanism for this conversion starting with Schiff base PLP-ENZ. Remember to name the resulting alpha-keto acid.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter10: From Proteins To Phenotypes
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Problem 14QP: If phenylalanine was not an essential amino acid, would diet therapy (the elimination of...
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When alanine undergoes transamination with
oxaloacetate, alanine is first converted to alpha-keto
acid. The enzyme uses PLP as a cofactor. Suggest a
mechanism for this conversion starting with Schiff
base PLP-ENZ. Remember to name the resulting
alpha-keto acid.
Transcribed Image Text:When alanine undergoes transamination with oxaloacetate, alanine is first converted to alpha-keto acid. The enzyme uses PLP as a cofactor. Suggest a mechanism for this conversion starting with Schiff base PLP-ENZ. Remember to name the resulting alpha-keto acid.
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