Ascorbic acid: What does it mean to say that ascorbic acid is a strong reducing agent? What is the active form of ascorbic acid in plasma and how is it formed? How can we distinguish the various oxidation states of ascorbic acid?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter20: Electron Transport And Oxidative Phosphorylation
Section: Chapter Questions
Problem 16P
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    1. Ascorbic acid:
    • What does it mean to say that ascorbic acid is a strong reducing agent?
    • What is the active form of ascorbic acid in plasma and how is it formed?
    • How can we distinguish the various oxidation states of ascorbic acid?
    • Using chemical symbols or structures, illustrate the reducing activity of ascorbate in forming ascorbyl radical and dehydroascorbic acid
    • Why do we refer to the ascorbate/ascorbyl-radical/dehydroascorbate system as a reversible redox system?
    • Explain the role of ascorbic acid in:
    • Collagen synthesis
    • Iron absorption
    • Regeneration of a-tocopherol
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