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- Using a mouse as a model organism to study a multigenic order like type two diabetes is a waste of researchers’ time since mice do not contain the same genes found in humans. Agree/Disagree? Answer and explain here:Considering that you manipulated a zebrafish embryo by injecting high levels of retinoic acid so that no anterior genes will be expressed. Surprisingly, after embryonic development, you are still able to observed the presence of anterior structures. What could explain this observation, does this mean any errors has been committes( provide a specific answer or postulatiom of why it happened)? What changes in your experiment would you make to achieve your objective?For the expression of traits gene provide only the potentialily and the environment provides the opportunity.comment on the statement?
- Discuss why a genetic disease might have a particular age of onset.Would an infectious disease have an age of onset? Explain why orwhy not.Explain how the technique of replica plating supports the randommutation theory but conflicts with the physiological adaptationhypothesis.Can you suggest how we could have determined whether Bill’s aunts were carriers of the mutant BTK gene? Give the name for the procedure and brief explanation of how it’s done and the anticipated results. What controls would be needed?
- Besides the reasons listed in this feature,what other reasons would make the peaplant a better object for genetic study thanhumans?Traditional gene mapping has been applied successfully to a variety of organisms including yeast, fungi, maize, and Drosophila. However, human gene mapping has only recently shared a similar spotlight. What factors have delayed the application of traditional gene-mapping techniques in humans?Suppose a 10-year old patient has come to your office with a very rare disease. One so rare that only 100 people for the past 100 years have been diagnosed and nobody knows the gene or genes that are mutated in this disease. Describe the gene sequencing toold you would use to identify the mutated gene or genes in this hypothetical disease.
- . In browsing through the chimpanzee genome, you findthat it has three homologs of a particular gene, whereashumans have only two.a. What are two alternative explanations for thisobservation?b. How could you distinguish between these twopossibilities?Give typed explanation of all subparts otherwise leave itSuppose you found two classes of mouse mutations, one that affectedlimb development only and one that affected both limb and kidneydevelopment. Which class would be more likely to alter the functionof monocilia? Explain.
