Which enzyme is the major regulatory control point for Boxidation? a. carnitine acyl transferase I b. pyruvate carboxylase c. enoyl-CoA isomerase d. methylmalonyl-CoA mutase e. acetyl- CoA dehydrogenase
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- Not all of the acetyl-CoA from the mitochondria is carboxylated to malonyl-CoA because some are used in the? a.ß-oxidation cycles b.production of ATP c.priming step of the fatty acid biosynthesis d.conversion to pyruvateThe sources of the three (3) carbons in malonyl-Coa is/are: a. 1 C from C02 and 2 C from acetyl-CoA b. 1 C from HCO3- and 2 C from acetyl-CoA c. 1 C from biotin and 2 C from acetyl-CoA d. All three C from acetyl-CoAStatin drugs are used to treat hypercholesterolemia because they a. prevent cholesterol from inserting in plasma membranes b. prevent cholesterol ester formation c. inhibit HMG-CoA reductase d. stimulate HMG-CoA synthase
- The reaction of acetyl-CoA and oxaloacetate in the TCA cycle forms a. 5-carbon α-ketoglutarate b. 4-carbon Succinyl-CoA c. 6-carbon citrate d. 6-carbon α-ketoglutarate e. 4-carbon citrateExplain the difference of carbohydrate (glycolysis) from lipid (β-oxidation) metabolism in terms of producing an acetyl-coA that will enter the Kreb cycle?How similar of an effect would a mutation in pyruvate dehydrogenase have, compared to a mutation in pyruvate carboxylase that blocks its ability to be regulated by acetyl-CoA?
- Acetyl-CoA carboxylase is inhibited by A. biotin B. citrate C. acetyl-CoA D. palmitateWhat enzyme is inhibited by the group of medications known as statins? a)HMG-CoA synthase b)Aromatase c)Fatty acid synthase d)CyclooxygenaseIdentify the Krebs cycle enzyme that consumes a six-carbon substrate molecule, producing a six-carbon product molecule, but neither consumes nor produces NADH? A. a-ketoglutarate dehydrogenase B. isocitrate dehydrogenase C. succinyl CoA synthetase D. malate dehydrogenase E. aconitase
- When one acetyl CoA is processed through the citric acid cycle, how many times does each of the following events occur? a. A FAD molecule is a reactant. b. A CoA-SH molecule is produced. c. A dehydrogenase enzyme is needed for the reaction to occur. d. A C5 molecule is produced.Where does the carbon come from that is used to synthesize ketone bodies? a) Acetyl-CoA generated by decarboxylation of pyruvate b) Acetyl-CoA generated by deamination of amino acids c) Acetyl-CoA generated by beta-oxidation of fatty acids.Which of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenase