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Which group of side chains is most likely to take part in the catalysis during an enzymatic reaction? Substantiate the answer.

Which group of side chains is most likely to take part in the catalysis during an enzymatic reaction? Substantiate the answer.

Organic Chemistry
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter22: Reactions Of Benzene And Its Derivatives
Section: Chapter Questions
Problem 22.51P
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Which group of side chains is most likely to take part in the catalysis during an enzymatic reaction? Substantiate the answer.
Non-polar side chains Polar side chains -R Amino acid -R Amino acid Alanine Negative charge at pH 7 -CH3 Aspartic acid (Asp) (D) (Ala) (A) -CH2C. -CH.CH3 Valine Glutamic Acid (Val) (V) -CH2CH2C: (Glu) (E) CH3 Positive charge at pH 7 -CH2CH.CH3 -(CH2)4 NH3 Lysine (Lys) (K) Leucine (Leu) (L) CH3 -(CH2)3 NHC.NH, Arginine (Arg) (R) * NH2 --CH.CH2CH3 Uncharged at pH 7 Isoleucine Glycine (Gly) (G) (Ile) (I) -H CH3 Serine -CH2OH Phenylalanine (Phe) (F) -CH2 (Ser) (S) -CH.CH3 Threonine OH (Thr) (T) -CH2 Tryptophan (Trp) (W) Cysteine (Сys) (C) -CH2SH N H Tyrosine (Тyг) (Ү) -CH, FOH Methionine -CH2CH2 -S-CH3 (Met) (M) -CH,C `NH2 Asparagine (Asn) (N) CH.CO2 Proline -CH2CH,C Glutamine (Pro) (P) NH2 (Gln) (Q) Histidine HN N. H2 (complete structure) (His) (H) -CH,
Transcribed Image Text:Non-polar side chains Polar side chains -R Amino acid -R Amino acid Alanine Negative charge at pH 7 -CH3 Aspartic acid (Asp) (D) (Ala) (A) -CH2C. -CH.CH3 Valine Glutamic Acid (Val) (V) -CH2CH2C: (Glu) (E) CH3 Positive charge at pH 7 -CH2CH.CH3 -(CH2)4 NH3 Lysine (Lys) (K) Leucine (Leu) (L) CH3 -(CH2)3 NHC.NH, Arginine (Arg) (R) * NH2 --CH.CH2CH3 Uncharged at pH 7 Isoleucine Glycine (Gly) (G) (Ile) (I) -H CH3 Serine -CH2OH Phenylalanine (Phe) (F) -CH2 (Ser) (S) -CH.CH3 Threonine OH (Thr) (T) -CH2 Tryptophan (Trp) (W) Cysteine (Сys) (C) -CH2SH N H Tyrosine (Тyг) (Ү) -CH, FOH Methionine -CH2CH2 -S-CH3 (Met) (M) -CH,C `NH2 Asparagine (Asn) (N) CH.CO2 Proline -CH2CH,C Glutamine (Pro) (P) NH2 (Gln) (Q) Histidine HN N. H2 (complete structure) (His) (H) -CH,
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