Answered: Which of the following bases are strong…

Which of the following bases are strong enough to deprotonate CH3CH2CH2C≡CH (pKa = 25) so that equilibrium favors the products: (a) H2O; (b) NaOH; (c) NaNH2; (d) NH3; (e) NaH; (f) CH3Li?

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions

Section19.SE: Something Extra

Problem 28VC

See similar textbooks

Related questions

Q: amidase NH2 HO, NH + K dabvana cocuai unt fan onzim amidace

Q: Draw the products of the pentanoic acid + PBr3 + Br2, followed by hydrolysis

A: The reaction is as follows:

Q: Propose a reagent for the conversion of (B) to (C).

A: This reaction will be a type of condensation reaction as in the reactant side we will be take an…

Q: The rate constant for the uncatalyzed reaction of two molecules of glycine ethyl ester to form…

Q: H H C-C-NH, H ČOOH Tyrosine но Typine bydronyle H H C-C-NH, но Dopa HO ČOOH L-Aromatic amine acid…

Q: Treatment of cholesterol with MCPBA results in formation of a single epoxide A, with the…

A: Stereoselectivity is the property of a Compound or reaction in which a single reactant forms an…

Q: Write out a scheme for the resolution of the two enantiomers of the antiplatelet drug clopidogrel…

A: The stereogenic center of clopidogrel and 10-camphorsulfonic acid are shown in figure 1.

Q: What products are formed when mCPBA reacts with the following compound. Indicate which is the major…

A: The product is as follows:

Q: One pathway for the metabolism of D-glucose 6-phosphate is its enzyme-catalyzed conversion to…

A: Enzyme catalysed conversion of D-glucose-6-phophate to D-fructose 6-phosphate

Q: Synthesize the o-form of amino benzoic acid from benzene.

A: Synthesis of o-form of amino benzoic acid from benzene is given below

Q: Draw the mechanism for the following acid/base reactions. Give the direction of the equilibrium…

A: The following are the mechanisms:

Q: Provide the product of the following reaction, by writing the nume O Br HOCH₂CH₂OH H₂SO4 Mg.

Q: Draw the organic products formed in each reaction.

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 1) 0,; CH,CI,; -78°C 2) Zn; ácido acético 1) O,; CH,CI,; -78°C 2) Zn; ácido acético 1) O,: CH,CI;…

Q: Identify what kind of compound B would be. CH3COOH + PC13 A + Acetic acid/Pyridine --> B oAldehyde o…

A: Please find below the reaction taking place.

Q: 4) 4- Customized synthesis of carbohydrate compounds is a popular area of research. Complete the…

A: We have to draw following given reactions in a stepwise for (D)-glucopyranose as follows in step 2:

Q: 3.) Based on the structure of its conjugate base, which acid has the lowest pK,? A. CH3COOH B.…

Q: Which of the reactions are spontaneous (favorable)? Rh(I) C,H, + H, C,H. AG = -150.97 kJ/mol…

A: R∆G of each reactions is given. Spontaneous reaction / reactions = ?

Q: Which of the following is an electrophile ? O H₂O O HO™ O CI O CH3NH2 O CH3CH2

A: Electrophile is the species which has lack of electron density i.e. electron deficient species.here…

Q: Which of the following is (2R,3R)-diaminobutane? CH, H-NH H,N-H CH, CH, H,N H H,NH CH H十NH H NH CH,…

A: The correct option with explanation is provided below:

Q: e 1hह बेटेवोस्ठे एवुपककीनक लिउ किर धुोण्या छण जहवतनीक है मर भnehamisn उनकर वी बच्ेकेकरांलन नेमर…

A: The given reaction is aquation of carbonato complex in the presence of H+. Labelled water is used…

Q: 2) Write the products of the following reactions and indicate if they are meso compounds or racemic…

A: Both the reaction give meso compound because in both reaction their should be syn addition and after…

Q: Do the equilibria of the following acid–base reactions lie to the right or the left? (The pKa of…

A: A reaction is said to be in equilibrium if the rate of the forward reaction is equal to the rate of…

Q: Determine the X in Stork enamine synthesis. HO H₂ C CH 'N H P-TOH (- H2O) > X20 Gultur

A: As we know that, Ketone or Aldehyde react with amine to form Enamine. Overall process called as…

Q: Draw the organic products formed in attached reaction, and indicate the stereochemistry of products…

A: Organic reactions are reactions involving organic compounds. The types of reactions seen in organic…

Q: Explain why, when the imidazole ring of histidine is protonated, the double-bonded nitrogen is the…

A: Proton which is close to acidic group will be protonated first therefore proton(NH2) near to COOH…

Q: H2. Pd 25° C, 3atm e) Reaction type Stereochemical Relationship Mechanism: H20, H2SO4 f) Reaction…

A: E. Cis hydrogenation : Hydrogen is added bottom of the face or top face results enantiomers. F.…

Q: Provide hrecereet Prud uct Br koH noreathon

A: There are number of functional group associated with organic compounds which impart specific…

Q: The enzyme that catalyzes the C-Cg bond cleavage reaction that converts serine to glycine removes…

A: The chemical structure for PLP, serine, and glycine is shown below.

Q: a) 1) TSCI, pyridine 2) 0 K b) 1)NaSCH,CH, 2) H,0 OCH, c) Brz OCH, d) PBI

A: ->In E2 elimination reaction antiperiplanar beta hydrogen eliminated. ->nucleophile can open…

Q: Psilocybin is a hallucinogenic compound found in some mushrooms. Present a straightforward pathway…

Q: A graduate student was studying enzymatic reductions of cyclohexanones when she encountered some…

A: When cyclohexanone is reacted with NaDPH and enzyme to formed the reduced product that is optically…

Q: Which of the following produces only butanoic acid (CH3CH2CH2 CO2H) being 'hydrolyzed in acid…

Q: Write out a scheme for the resolution of the two enantiomers of the antiplatelet drug clopidogrel…

A: The stereogenic center of clopidogrel and 10-camphorsulfonic acid are shown in figure 1.

Q: The following compound has been found to be an inhibitor of penicillinase. The enzyme can be…

A: Penicillinase is an enzyme that provides resistance to penicillin by using CH2OH group to open the…

Q: Ester group (e.g. -CO2Et) is considered a .... Ortho/Para Directing Activator Ortho/Para Directing…

Q: Ribose, a carbohydrate with the formula shown, forms a cyclic hemiacetal, which, in principle, could…

A: The isomeric cyclic acetals A and B are shown as follows:

Q: Draw the structure(s) of the major organic product(s) of the following reaction. Dilute aqueous NaOH…

A: The given reaction is as follows,

Q: What is the major neutral organic product for the following sequence? SOCI, 1. ? pyridine OH 2.…

Q: Explain why, when the imidazole ring of histidine is protonated, the double-bonded nitrogen is the…

Q: Draw resonance forms for the sigma complexes resulting from electrophilic attackon substituted…

Q: A chemist synthesized compound X as a racemic mixture. When the ketone group in X was enzymatically…

A: Given: A reaction takes place in which a racemic mixture gives a single product with 100% yield. To…

Q: :NH2 NH3 NH, CN hydrolysis CN R coo e-amino acids can be prepared by the Strecker zpathesis, a…

A: Strecker's synthesis is widely used in the production of o-aminonitriles. It consists of two steps…

Q: 4. Tryptophan can also form adducts with arenediazonium ions, although the reaction is not…

A: Here the chemical reaction is:

Q: Which statement below is incorrect? O In imidazole, each N atom contributes one electron to the…

A: By drawing the struture of molecules we can identify incorrect statement.

Q: 5. The enantiomers of 1-amino-2-propanol were separated and recovered as their hydrochloride salts:…

A: a. Streochemical formula for the both isomers are shown as below: b.The enantiomers can rotate the…

Q: wh काय ताप्ही जवा धुरथ्वे करीप me ला शोंण्ट ककड़ण्OT w नैसेवानशव. Sleet one or more (ब) Pठि०५ Vवनंर…

A: In the given reaction, the phosphate group (-PO42-) from phosphoenolpyruvate(PEP) is transferred to…

Q: Assign an E or Z configuration to these dicarboxylic acids, each of which is an intermedi- ate in…

A: The IUPAC system for naming alkene isomers, called the E-Z system, is based on the same priority…

Q: Identify the overlapping orbitals involved in the formation of each numbered bond.

A: Here we are given two molecules and in this we are mentioned 7 type of bonds and we have to write…

Question

Which of the following bases are strong enough to deprotonate CH₃CH₂CH₂C≡CH (pK_a = 25) so that equilibrium favors the products: (a) H₂O; (b) NaOH; (c) NaNH₂; (d) NH₃; (e) NaH; (f) CH₃Li?

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

Step 2

Step 3

Step 4

Trending now

This is a popular solution!

Step by step

Solved in 4 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

The rate constant for the uncatalyzed reaction of two molecules of glycine ethyl ester to form glycylglycine ethyl ester is 0.6 M-1s-1. In the presence of Co2+, the rate constant is 1.5 x 106 M-1s-1. What rate enhancement does the catalyst provide?
Polyunsaturated fatty acids (PUFA's) in oils 0.g. sunflower oil are prone to rancidity because they contain conjugated double bond systems which are easily oxidized in the presence of light or peroxides. BHT Is used as an antioxidant in oils to prevent oxidative rancidity. How do BHT prevent oils from reacting with peroxides so that they do not become rancid? Show the mechanism.
Ammonia (NH3) is a weak base that under acidic conditions becomes protonated to the ammonium ion in thefollowing reaction:NH3 + H+ → NH4 +NH3 freely permeates biological membranes, including thoseof lysosomes. The lysosome is a subcellular organelle witha pH of about 4.5–5.0; the pH of cytoplasm is about 7.0.What is the effect on the pH of the fluid content of lysosomes when cells are exposed to ammonia? Note: Ammonium (NH4 +) does not diffuse freely across membranes.
CaC2O4 + KMnO4 (in the presence of H2SO4)
The rate constant for the uncatalyzed reaction of two molecules of glycine ethyl ester to form glycylglycine ethyl ester is 0.6 M- 1s - 1. In the presence of Co2 +, the rate constant is 1.5 * 106 M- 1s - 1. What rate enhancement does the catalyst provide?
Determining if a Base Is Strong Enough to Deprotonate an Acid Which of the following bases is strong enough to deprotonate N,Ndimethylacetamide [CH3CON(CH3)2, pKa = 30], so that equilibrium favors the products:(a)NaNH2; (b) NaOH?
Which of the compounds have the lowest pKA, why?
If the pKa values for the bases were given, I would know how to solve this but how can I know just by looking at them? Which of the following bases are strong enough to deprotonate CH3CH2CH2C≡CH (pKa = 25), so that equilibrium favors the products? CF3COONa CH3CH2Li NaC≡N NaNH2 NaOH NaH
what is the structure of o-methylphenoxide anion and what is its pKa?
Which of the following bases is strong enough to deprotonate N,Ndimethylacetamide [CH3CON(CH3)2, pKa = 30], so that equilibrium favors the products: (a) NaNH2; (b) NaOH?
The pKa values of the carboxylic acid groups of oxaloacetic acid are 2.22 and 3.98. a. Which carboxyl group is the stronger acid? b. The amount of hydrate present in an aqueous solution of oxaloacetic acid depends on the pH of the solution: 95% at pH 0, 81% at pH 1.3, 35% at pH 3.1, 13% at pH 4.7, 6% at pH 6.7, and 6% at pH 12.7. Explain this pH dependence.
Please answer 22b c both.