Which of the following is a limitation of the Friedel-Crafts reaction? Select one: OA. The carbocation electrophile can potentially undergo an unwanted rearrangement prior to its bonding to the aromatic ring. O B. Poly-alkylation products form when aromatic reactant and alkylating agent are mixed together in comparable amounts. OC. A Friedel-Crafts reaction fails when the aromatic starting compound contains a moderately or strongly deactivating group. OD. All of the above choices are limitations of the Friedel-Crafts reaction.

Which of the following is a limitation of the Friedel-Crafts reaction? Select one: OA. The carbocation electrophile can potentially undergo an unwanted rearrangement prior to its bonding to the aromatic ring. O B. Poly-alkylation products form when aromatic reactant and alkylating agent are mixed together in comparable amounts. OC. A Friedel-Crafts reaction fails when the aromatic starting compound contains a moderately or strongly deactivating group. OD. All of the above choices are limitations of the Friedel-Crafts reaction.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 31CTQ

See similar textbooks

Similar questions

In Image 4 predict the effect the substituent attached to the benzene ring would have on electrophilic aromatic substitution reactions? a.ortho/para director, deactivator b.ortho/para director, activator c.meta director, activator d.meta director, deactivator
Which rearrangement product will form preferentially during the [1,2]-rearrangementof an R-group? Motivate.
The use of curved arrows is a powerful tool that illustrates even complex reactions. a.Add curved arrows to show how carbocation A is converted to carbocation B. Label each new σ bond formed. Similar reactions have been used in elegant syntheses of steroids. b.Draw the product by following the curved arrows. This reaction is an example of a [3,3] sigmatropic rearrangement, as we will learn in Chapter 25.
Reactions are impacted by various factors that depend on the mechanism of the reaction.Some of the variables for substitution reactions are: • strength of the nucleophile • concentration of the nucleophile • leaving group ability (i.e., is it a “bad” or a “good” leaving group?In an SN2 reaction, the nucleophile forces the leaving group to leave. (This is the rate-determining step of the reaction.)In an SN1 reaction, the nucleophile does not attack until the leaving group has left. (When the leaving group leaves, this is the rate-determining step of the reaction.) Based on the information provided in this question, which factors would favor an SN2 reaction? a strong nucleophile a good leaving group a high concentration of nucleophile
Reactions are impacted by various factors that depend on the mechanism of the reaction.Some of the variables for substitution reactions are: • strength of the nucleophile • concentration of the nucleophile • leaving group ability (i.e., is it a “bad” or a “good” leaving group?In an SN2 reaction, the nucleophile forces the leaving group to leave. (This is the rate-determining step of the reaction.)In an SN1 reaction, the nucleophile does not attack until the leaving group has left. (When the leaving group leaves, this is the rate-determining step of the reaction.) Based on the information provided in this question, which factors would favor an SN2 reaction?Choose one or more: A.a strong nucleophile B.a good leaving group C.a high concentration of nucleophile Based on the information provided in this question, which factors would favor an SN1 reaction?Choose one or more: A.a strong nucleophile B.a good leaving group C.a high concentration…
Rank the attached dienophiles in order of increasing reactivity.
Consider the following alkyl halides: - may react with NaI to give JKL? - an alkyl iodide that will give SN1 and E1 product? - has the highest boiling point? - most likely to give retention and inversion products in SN1 reaction? - most likely to give rearrangement product in SN1?